In the context of physical systems, tissues are hierarchically organized assemblies of cells and extracellular matrix that exhibit emergent mechanical, transport, and signaling properties distinct from those of their individual components. They function as active, viscoelastic materials capable of growth, remodeling, force generation, and collective migration, governed by mechano-chemical feedback and spatial patterning. Tissue-level behavior arises from cell–cell and cell–matrix interactions, including adhesion, cytoskeletal dynamics, and morphogen gradients, and can be modeled using continuum mechanics, active matter frameworks, or agent-based approaches to capture processes such as morphogenesis, homeostasis, and mechanotransduction in developmental and physiological systems.
Researchers have developed a new class of ultra-thin, flexible bioelectronic material that can seamlessly interface with living tissues. They introduced a novel device called THIN (transformable and imperceptible hydrogel-elastomer ...
Bio & Medicine
Dec 10, 2025
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154
Cells convert mechanical forces into signals that influence physiological processes, such as exercise strengthening bones. A research team at Washington University in St. Louis and Tsinghua University in Beijing have discovered ...
Cell & Microbiology
Nov 3, 2025
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54
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial transcriptomics. Trained on ...
Cell & Microbiology
Nov 3, 2025
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29
Human health is the Achilles heel of space travel. Researchers at ETH Zurich have now succeeded in printing complex muscle tissue in zero gravity. This will enable drugs for space missions to be tested in the future.
Space Exploration
Oct 31, 2025
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131
To explore possible treatments for various diseases, either animal models or human cell cultures are usually used first; however, animal models do not always mimic human diseases well, and cultures are far removed from tissue ...
Bio & Medicine
Sep 29, 2025
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44
The field of tissue engineering aims to replicate the structure and function of real biological tissues. This engineered tissue has potential applications in disease modeling, drug discovery, and implantable grafts.
Biotechnology
Sep 18, 2025
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50
Cells bumping against one another use electricity to identify which of their neighbors has the least energy to expel them. The King's College London study in partnership with the Francis Crick Institute provides insight into ...
Cell & Microbiology
Sep 10, 2025
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128
A tissue fold known as the cephalic furrow, an evolutionary novelty that forms between the head and the trunk of fly embryos, plays a mechanical role in stabilizing embryonic tissues during the development of the fruit fly ...
Evolution
Sep 3, 2025
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26
Zebrafish midline tissues coordinate their growth during embryonic development using a leader-follower strategy described by formation control, as reported by researchers from Japan and the U.S. The notochord leads elongation, ...
Cell & Microbiology
Aug 26, 2025
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17
In wound healing, immune response, and cancer metastasis, cells migrate through the body—often squeezing through narrow, confined spaces. Together with experimental collaborators, Professor David Bruckner at the University ...
Cell & Microbiology
Aug 26, 2025
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52
