In the context of physical systems, tissues are hierarchically organized assemblies of cells and extracellular matrix that exhibit emergent mechanical, transport, and signaling properties distinct from those of their individual components. They function as active, viscoelastic materials capable of growth, remodeling, force generation, and collective migration, governed by mechano-chemical feedback and spatial patterning. Tissue-level behavior arises from cell–cell and cell–matrix interactions, including adhesion, cytoskeletal dynamics, and morphogen gradients, and can be modeled using continuum mechanics, active matter frameworks, or agent-based approaches to capture processes such as morphogenesis, homeostasis, and mechanotransduction in developmental and physiological systems.
Embryonic development is one of the most dynamic biological processes in nature. Cells and tissues organize and reorganize themselves following incredibly precise patterns, while remaining flexible and robust. Scientists ...
Cell & Microbiology
22 hours ago
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How did life make the leap from single cells to coordinated, multicellular organisms? And how do genetically identical cells still perform a version of that feat every time an embryo begins to take shape?
Evolution
Jun 2, 2026
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A team of Israeli scientists at the Hebrew University of Jerusalem has developed a novel method to significantly lower the production costs of cultivated meat. The new study demonstrates that preloading plant-derived cellulose ...
Cell & Microbiology
Jun 2, 2026
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From the revived corpse of Frankenstein's monster to the disembodied hand, "Thing," in the Addams Family, reanimated tissue is one of the most enduring images in science fiction. It turns out, that image has some basis in ...
Cell & Microbiology
May 27, 2026
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A core challenge in biology is understanding how processes in the body, such as cellular development and regeneration, unfold over long stretches of time, making them notoriously difficult to view at the molecular level. ...
Cell & Microbiology
May 27, 2026
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Researchers from the National University of Singapore (NUS) have discovered that cancer cells do not simply push through surrounding tissues to spread, but instead actively grip onto protective tissue barriers and pull them ...
Cell & Microbiology
May 12, 2026
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Scientists have discovered how cells decide when to respond to physical forces, potentially opening new avenues for tackling diseases such as cancer and fibrosis.
Cell & Microbiology
Apr 29, 2026
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In tissue engineering, the tiniest bit of improper force can harm a living culture. Spheroids—3D clumps of cells—can be used to model complex human tissues, because they can re-create specific cell-to-cell and cell-to-matrix ...
Cell & Microbiology
Apr 28, 2026
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Understanding how wounds heal after injury could be a step closer thanks to a new mathematical model developed by researchers at the University of Bristol. The study, published in Physical Review Letters, builds on previous ...
Cell & Microbiology
Apr 27, 2026
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Biological tissues have a remarkable ability to organize and change shape, driven by forces generated by their own cells. One of the major challenges in bioengineering is harnessing this natural behavior to design synthetic ...
Cell & Microbiology
Apr 16, 2026
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