Research news on Synthesis

Synthesis as a research area encompasses the development and optimization of methods to construct complex entities from simpler precursors, typically in chemistry, materials science, and related disciplines. It focuses on designing reaction pathways, controlling selectivity, yield, and functional group compatibility, and enabling the scalable preparation of target molecules or materials with defined structures and properties. This area includes methodological innovation (e.g., new catalytic systems, green and sustainable protocols, automated or high-throughput synthesis) and integrates analytical, mechanistic, and computational tools to refine synthetic routes. Synthesis research underpins the creation of pharmaceuticals, functional materials, and molecular probes essential for experimental science.

Designing better membrane proteins by embracing imperfection

Scientists at the VIB–VUB Center for Structural Biology have uncovered a counterintuitive principle that could reshape how membrane proteins are designed from scratch: Sometimes, making a protein less stable helps it fold ...

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