Research news on Surfactants, micelles & vesicles

Surfactants, micelles, and vesicles constitute a class of self-assembled soft-matter physical systems arising from amphiphilic molecules in solution. Above the critical micelle concentration, surfactants spontaneously form micelles, typically spherical or anisotropic aggregates with hydrophobic cores and hydrophilic coronas, governed by minimization of interfacial free energy and packing constraints. At higher concentrations or appropriate conditions (e.g., temperature, ionic strength, tail architecture), these assemblies can transition into bilayer-based vesicles, closed shell structures encapsulating aqueous volumes and exhibiting bending elasticity, membrane tension, and permeability properties. Collectively, these systems serve as model platforms for studying interfacial thermodynamics, mesoscale organization, and transport phenomena in complex fluids.

Designing better membrane proteins by embracing imperfection

Scientists at the VIB–VUB Center for Structural Biology have uncovered a counterintuitive principle that could reshape how membrane proteins are designed from scratch: Sometimes, making a protein less stable helps it fold ...

New imaging technique maps membrane lipids in 3D at nanoscale

Biological membranes of cells and their subunits (organelles) are organized into tiny regions (nanodomains) made up of fats (lipids) and proteins. Those specialized regions carry out important tasks for the cell, such as ...

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