Research news on Species Specificity

Species specificity, as a biological process, refers to the selective interaction, compatibility, or functional activity of biological molecules, cells, or pathogens with organisms of particular species, arising from co-evolved structural and regulatory determinants. It encompasses mechanisms such as species-restricted receptor–ligand recognition, host-range determinants in pathogens, species-dependent expression or sequence variants of target proteins, and immune recognition constraints that limit cross-species functionality. Species specificity thus governs processes like host tropism, cross-species transmission barriers, xenogeneic incompatibilities, and the species-selective efficacy or toxicity of biomolecules, ultimately shaping interspecies boundaries in infection, signaling, and physiological regulation.

A 'stemness checkpoint' helps control stem cell identity

A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages. For nearly two decades, ...

Viruses 'eavesdrop' on each other—but it can backfire

University of Exeter scientists studied chemical communication by phages (viruses that infect bacteria). The phages assessed in the study have two choices when they enter a cell: lie dormant or kill the cell and release new ...

page 1 from 3