Sample preparation is a fundamental laboratory technique encompassing all procedures required to convert a raw specimen into a form suitable for analytical measurement or experimental manipulation, while preserving analyte integrity and representativeness. It typically includes sampling, homogenization, separation, purification, concentration, and, when necessary, chemical derivatization. Methods vary by matrix and analytical modality (e.g., filtration, centrifugation, extraction, digestion, or fixation for microscopy), and are optimized to minimize contamination, losses, matrix effects, and chemical transformations. Rigorous sample preparation is critical for achieving accuracy, precision, sensitivity, and reproducibility in techniques such as chromatography, mass spectrometry, spectroscopy, and molecular biology assays.
In a paper published recently in the Journal of Applied Physics, an international team of scientists from Lawrence Livermore National Laboratory (LLNL), Argonne National Laboratory and Deutsches Elektronen-Synchrotron have ...
General Physics
Aug 28, 2024
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88
A research team has developed a double-layer dry transfer printing technology that simultaneously transfers light-emitting and electron-transferring layers onto a substrate. This technology is expected to provide a more life-like ...
Optics & Photonics
Aug 22, 2024
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114
A view into how nanoscale building blocks can rearrange into different organized structures on command is now possible with an approach that combines an electron microscope, a small sample holder with microscopic channels, ...
Nanomaterials
Aug 19, 2024
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82
A study, led by Tingting Zuo, was based on the idea of in-situ growth, and a series of Cu/Gr composites with improved interfaces were prepared by vacuum hot press sintering. Combined with cold-drawing and heat-treatment processes, ...
Nanomaterials
Jun 24, 2024
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130
National University of Singapore (NUS) researchers have developed a novel phase-selective in-plane heteroepitaxial strategy for growing two-dimensional transition metal dichalcogenides (2D TMDs). This approach provides a ...
Nanomaterials
May 23, 2024
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99
Large-area flexible transparent conductive films (TCFs) are urgently needed for future electronics, optoelectronics, energy devices and other fields. Indium tin oxide (ITO) TCF, which is widely used in modern technology, ...
Nanomaterials
May 23, 2024
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59
An international collaborative study that features researchers from Tel Aviv University (TAU), presented a new method for growing ultra-long and ultra-narrow strips of graphene (a derivative of graphite), which exhibit semiconducting ...
Nanomaterials
May 20, 2024
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135
Nanoscale materials present us with astonishing chemical and physical properties that help materialize applications such as single molecular sensing and minimally invasive photothermal therapy—which were once just theories—into ...
Nanomaterials
May 7, 2024
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291
A technology enabling the fabrication of intricate three-dimensional (3D) quantum dot (QD)-based structures at room temperature has been developed.
Nanomaterials
May 2, 2024
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70
With every new particle accelerator built for research, scientists have an opportunity to push the limits of discovery. But this is only true if new particle accelerators deliver the desired performance—no small feat in a ...
General Physics
Apr 18, 2024
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96
