Regeneration is a biological process by which organisms restore or replace lost or damaged tissues, organs, or body parts through controlled cell proliferation, differentiation, and patterning. It involves activation of resident stem or progenitor cells, dedifferentiation of mature cells in some taxa, and re-establishment of appropriate positional information via morphogen gradients and signaling pathways such as Wnt, FGF, BMP, and Notch. Regeneration can be epimorphic, with blastema formation and large-scale pattern reconstruction, or morphallactic, involving extensive tissue remodeling. Its extent and fidelity are species- and tissue-specific, constrained by genetic programs, immune responses, and age-dependent changes in cellular plasticity.
A recent study published in Nano Letters has introduced a new method for delivering particles into stem cells, which are notoriously difficult to penetrate. The discovery will make it easier to direct and enhance the processes ...
Bio & Medicine
May 9, 2023
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Therapeutics that use mRNA—like some of the COVID-19 vaccines—have enormous potential for the prevention and treatment of many diseases. These therapeutics work by shuttling mRNA "instructions" into target cells, providing ...
Bio & Medicine
Apr 3, 2023
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Technology developed by researchers at the Indiana University School of Medicine that can change skin tissue into blood vessels and nerve cells has also shown promise as a treatment for traumatic muscle loss.
Bio & Medicine
Nov 9, 2022
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A team of researchers from Singapore has reported the development of a skin-mimicking scaffold by parallelly aligning nanofibers made up of a mixture of polycaprolactone (PCL) and gelatin that enhances wound healing. Their ...
Bio & Medicine
Nov 4, 2022
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Hair loss is undesirable for many men—and women—because one's hairstyle is often closely tied to their self-confidence. And while some people embrace it, others wish they could regrow their lost strands. Now, researchers ...
Bio & Medicine
Oct 31, 2022
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The Indiana Center for Regenerative Medicine and Engineering (ICRME) at Indiana University School of Medicine is home to tissue nanotransfection (TNT) regenerative medicine technology that achieves functional tissue reprogramming ...
Bio & Medicine
Jul 18, 2022
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Within a newborn's umbilical cord lie potentially life-saving stem cells that can be used to fight diseases like lymphoma and leukemia. That is why many new parents elect to store ("bank") their infant's stem cell-rich umbilical ...
Bio & Medicine
Jul 8, 2022
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A study led by Prof. Qiuyu Zhang (Northwestern Polytechnical University), Prof. Ki-Bum Lee (Rutgers University), and Prof. Liang Kong (School of Stomatology, The Fourth Military Medical University) has established an injectable ...
Bio & Medicine
Apr 15, 2022
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A finding by UC Riverside bioengineers could hasten development of lab-grown blood vessels and other tissues to replace and regenerate damaged tissues in human patients. The results are published in ACS Applied Materials ...
Bio & Medicine
Apr 6, 2022
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Stem cells can develop into many different types of cells in the body. For instance, when a person is injured, stem cells come to the site of the injury and aid in healing damaged tissues. New nanotechnology developed by ...
Bio & Medicine
Mar 30, 2022
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