Regeneration is a biological process by which organisms restore or replace lost or damaged tissues, organs, or body parts through controlled cell proliferation, differentiation, and patterning. It involves activation of resident stem or progenitor cells, dedifferentiation of mature cells in some taxa, and re-establishment of appropriate positional information via morphogen gradients and signaling pathways such as Wnt, FGF, BMP, and Notch. Regeneration can be epimorphic, with blastema formation and large-scale pattern reconstruction, or morphallactic, involving extensive tissue remodeling. Its extent and fidelity are species- and tissue-specific, constrained by genetic programs, immune responses, and age-dependent changes in cellular plasticity.
Axolotls, with their signature smiles and pink gills, are the celebrities of the salamander world. But they are more than just cute: They might also hold the secret to regenerating human limbs.
Plants & Animals
Jun 10, 2025
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85
Imagine that doctors could precisely print miniature capsules capable of delivering cells needed for tissue repair exactly where they are needed inside a beating heart.
Bio & Medicine
May 8, 2025
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60
Northwestern Medicine investigators have developed first-of-its-kind eyedrops that use synthetic nanoparticles to help the eye regenerate cells that have been damaged by mustard keratopathy, or exposure to mustard gas, and ...
Bio & Medicine
May 7, 2025
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151
Queensland is widely known as the land clearing capital of Australia. But what's not so well known is many of the cleared trees can grow back naturally.
Environment
Apr 16, 2025
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21
The skin serves as the body's primary defense against harmful microorganisms, toxins, and physical damage. However, severe injuries from burns, trauma, surgery, or conditions like diabetes can compromise its ability to heal ...
Bio & Medicine
Feb 12, 2025
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77
A research team from the Eye & ENT Hospital of Fudan University, China, has developed a novel biocompatible nanoadhesive for corneal transplantation. The nanoadhesive is based on tetrahedral framework nucleic acids combined ...
Bio & Medicine
Feb 10, 2025
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29
Tissue engineering utilizes 3D printing and bioink to grow human cells on scaffolds, creating replacements for damaged tissues like skin, cartilage, and even organs. A team of researchers led by Professor Insup Noh from Seoul ...
Bio & Medicine
Feb 3, 2025
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184
A research team led by Dr. Du Xuemin from the Shenzhen Institutes of Advanced Technology (SIAT) of the Chinese Academy of Sciences has reported a living interface with unique functionalities of durable secretion of bioactive ...
Bio & Medicine
Nov 22, 2024
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36
Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed a revolutionary injectable granular filler that could transform the way diabetic wounds are treated, potentially improving patient outcomes. ...
Bio & Medicine
Oct 31, 2024
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23
Diabetes, a widespread condition affecting approximately 13% of American adults, is often accompanied by complications such as impaired wound healing. If left unchecked, this can lead to severe outcomes, including the need ...
Bio & Medicine
Sep 20, 2024
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78
