Pathology is the scientific discipline that investigates the mechanisms, structural alterations, and functional consequences of disease in organisms, integrating molecular, cellular, tissue, and organ-level analyses. It encompasses the study of etiological factors, pathogenesis, and morphologic changes, as well as the correlation of these changes with clinical manifestations. Modern pathology spans subfields such as anatomical pathology, which examines tissues and cells, and clinical pathology, which analyzes bodily fluids and molecular markers, often using techniques like histochemistry, immunohistochemistry, flow cytometry, and genomics. As a core biomedical science, pathology provides the conceptual and empirical framework for understanding disease processes and informing diagnosis, prognosis, and therapeutic strategies.
Diagnosing cancer and selecting the appropriate therapy depend crucially on how well experts understand the processes in tumors at the microscopic level. Central to this is understanding how cells in tissues communicate and ...
Cell & Microbiology
Oct 16, 2025
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21
Cells in our body are programmed to die after a certain period of time—a natural process known as apoptosis. This process is essential for maintaining the body's balance. When aged or damaged cells are not properly eliminated, ...
Cell & Microbiology
Sep 2, 2025
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16
New research, published in the journal Science, shows how lysosomes—organelles that act like cells' waste disposal system—respond to stress by becoming abnormally bloated, a process called lysosomal vacuolation that is associated ...
Cell & Microbiology
Aug 21, 2025
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25
A network analysis of more than 26,000 dogs and their health conditions helps reveal which diseases tend to go together, providing data that veterinarians and researchers can use to help treat the problems that dogs face, ...
Molecular & Computational biology
Aug 14, 2025
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32
Respiratory disorders in dogs can quickly become critical and are reported to be the second leading cause of cardiac arrest in canines. Therefore, it is necessary to take appropriate measures according to each patient's condition. ...
Veterinary medicine
Aug 6, 2025
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19
In Nature Ecology & Evolution, a group of researchers reveal the cause of sea star wasting disease (SSWD). This discovery comes more than a decade after the start of the marine epidemic that has killed billions of sea stars—representing ...
Ecology
Aug 4, 2025
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73
A research team led by the Leibniz-HKI in Jena has uncovered a new way in which the yeast Candida albicans can damage human tissue. In a study published in Nature Communications, the scientists describe an alternative pathogenicity ...
Cell & Microbiology
Jul 22, 2025
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41
Biopsies are clinical tools commonly used to diagnose a variety of diseases or to monitor tissue for abnormal growth or even rejection of a transplant. During biopsies, tissue samples are removed from the body so they can ...
Bio & Medicine
Jul 16, 2024
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75
The ability to detect diseases at an early stage or even predict their onset would be of tremendous benefit to doctors and patients alike. A research team led by Dr. Larysa Baraban at the Helmholtz-Zentrum Dresden-Rossendorf ...
Bio & Medicine
Feb 7, 2024
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134
Researchers from Brigham and Women's Hospital and the Massachusetts Institute of Technology (MIT) have unveiled unprecedentedly detailed images of brain cancer tissue through the use of a new microscopy technology called ...
Bio & Medicine
Jan 31, 2024
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