Molecular biology is a discipline within the life sciences that investigates biological processes at the level of molecules, primarily nucleic acids and proteins. It focuses on the mechanisms of DNA replication, repair, recombination, transcription, and RNA processing, as well as translation and post-translational modification of proteins. Molecular biology integrates concepts and methods from biochemistry, genetics, and cell biology, employing techniques such as cloning, PCR, sequencing, gene editing, and transcriptomic and proteomic profiling. It underpins contemporary research in areas including gene regulation, signal transduction, developmental biology, pathogen–host interactions, and the molecular basis of disease.
Investigators led by Francesca Elizabeth Duncan, Ph.D., the Thomas J. Watkins Memorial Professor of Reproductive Science, have discovered new molecular mechanisms that lead specialized immune cells to cause ovarian aging ...
Cell & Microbiology
Jul 21, 2025
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Unraveling the genetic mechanisms behind adaptive evolution stands as a pivotal challenge in molecular biology. While organisms often exhibit rapid phenotypic adjustments to environmental shifts, the underlying genomic processes ...
Evolution
Jul 18, 2025
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29
Researchers at Washington University School of Medicine in St. Louis have revealed the structure of a key protein involved in unspooling DNA so that it can undergo repair. Because this protein is critical for DNA repair for ...
Biotechnology
Jul 14, 2025
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16
While humans can escape the heat by seeking shade or shedding layers, plants remain rooted in place. So how do they survive extreme heat? It's a question many have wondered—and now, science has an answer.
Plants & Animals
Jul 14, 2025
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21
A new study published in Cell has unveiled a first-of-a-kind optogenetic screening platform, developed by scientists at Integrated Biosciences, a biotechnology company integrating optogenetics, chemistry and AI to discover ...
Biotechnology
Jul 14, 2025
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41
Molecular glues, tiny molecules that connect one protein to another, are promising targets for pharmaceutical research. By linking a disease-related protein to one that triggers a cell's demolition and recycling pathways, ...
The ability of protein kinases to transfer a phosphate group to target proteins plays an important role in many cellular processes. Scientists at the Max Planck Institute for Medical Research in Heidelberg have now developed ...
Biotechnology
Jul 10, 2025
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25
For decades, the central dogma of molecular biology—DNA makes RNA, RNA makes protein, protein makes phenotype—was the guiding framework for understanding inheritance and disease. This model explained classic Mendelian traits, ...
Every living cell must interpret its genetic code—a sequence of chemical letters that governs countless cellular functions. A new study by researchers from the Center for Theoretical Biological Physics at Rice University ...
Molecular & Computational biology
Jul 9, 2025
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105
By using a genetic technique developed at UT Southwestern Medical Center that forces cells to rid themselves of mitochondria, researchers are gaining new insights into the function of these critical organelles. Their findings, ...
Molecular & Computational biology
Jul 4, 2025
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