Molecular biology is a discipline within the life sciences that investigates biological processes at the level of molecules, primarily nucleic acids and proteins. It focuses on the mechanisms of DNA replication, repair, recombination, transcription, and RNA processing, as well as translation and post-translational modification of proteins. Molecular biology integrates concepts and methods from biochemistry, genetics, and cell biology, employing techniques such as cloning, PCR, sequencing, gene editing, and transcriptomic and proteomic profiling. It underpins contemporary research in areas including gene regulation, signal transduction, developmental biology, pathogen–host interactions, and the molecular basis of disease.
MicroRNAs (miRNAs) are valuable biomarkers for the diagnosis and prognosis of diseases. The 2024 Nobel Prize in Physiology or Medicine has been awarded to American scientists Victor Ambros and Gary Ruvkun for their discovery ...
Bio & Medicine
Oct 28, 2024
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A new molecular engineering technique can precisely influence the development of organoids. Microbeads made of specifically folded DNA are used to release growth factors or other signal molecules inside the tissue structures. ...
Bio & Medicine
Sep 9, 2024
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Dr. Petr Cígler and his collaborators are working on refining molecular systems for transporting ribonucleic acid (RNA) molecules into cells. The question of how to effectively deliver RNA to a designated place in the body ...
Bio & Medicine
May 15, 2024
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The delivery of experimental materials to individual cells with exactness and exclusivity has long been an elusive and much sought-after ability in biology. With it comes the promise of deciphering many longstanding secrets ...
Bio & Medicine
Feb 15, 2024
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Magnetic bacteria possess extraordinary capabilities due to the magnetic nanoparticles, the magnetosomes, which are concatenated inside their cells. A research team at the University of Bayreuth has now transferred all of ...
Bio & Medicine
Sep 21, 2023
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The RNA molecule is commonly recognized as messenger between DNA and protein, but it can also be folded into intricate molecular machines. An example of a naturally occurring RNA machine is the ribosome, that functions as ...
Bio & Medicine
Feb 27, 2023
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Messenger RNA (mRNA) are biological molecules that transfer the information coded by genes in the nucleus to the cytoplasm for protein synthesis by ribosomes. mRNA sequences can be designed to encode specific proteins; the ...
Bio & Medicine
Nov 10, 2022
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A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative ...
Bio & Medicine
Sep 8, 2022
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Constructing a tiny robot from DNA and using it to study cell processes invisible to the naked eye.... You would be forgiven for thinking it is science fiction, but it is in fact the subject of serious research by scientists ...
Bio & Medicine
Jul 28, 2022
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In "proof of concept" experiments with mouse and human cells and tissues, Johns Hopkins Medicine researchers say they have designed tiny proteins, called nanobodies, derived from llama antibodies, that could potentially be ...
Bio & Medicine
May 12, 2022
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