Research news on molecular biology

Molecular biology is a discipline within the life sciences that investigates biological processes at the level of molecules, primarily nucleic acids and proteins. It focuses on the mechanisms of DNA replication, repair, recombination, transcription, and RNA processing, as well as translation and post-translational modification of proteins. Molecular biology integrates concepts and methods from biochemistry, genetics, and cell biology, employing techniques such as cloning, PCR, sequencing, gene editing, and transcriptomic and proteomic profiling. It underpins contemporary research in areas including gene regulation, signal transduction, developmental biology, pathogen–host interactions, and the molecular basis of disease.

RNA-guided CRISPR system activates gene expression

In back-to-back studies published in Nature, researchers from Purdue University and Columbia University report a naturally evolved gene-editing system that can activate genes, offering an advantage over existing CRISPR gene-editing ...

How DICER cuts microRNAs with single-nucleotide precision

A research team from The Hong Kong University of Science and Technology (HKUST) has made an advance in understanding the molecular machinery of RNA silencing. The team uncovered how the human enzyme DICER achieves highly ...

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