Research news on mass spectroscopy

Mass spectroscopy is an analytical method for determining the mass-to-charge (m/z) ratios of ionized molecules or atoms to infer their molecular mass, composition, and structural features. In typical workflows, samples are ionized (e.g., by electron ionization, electrospray ionization, or MALDI), separated according to m/z in a mass analyzer (such as quadrupole, time-of-flight, ion trap, or Orbitrap), and detected to generate a mass spectrum. The method enables high-sensitivity, high-specificity characterization of complex mixtures, supports quantitative analyses through calibrated signal intensities, and is widely integrated with separation techniques (e.g., liquid or gas chromatography) to enhance resolution and analyte identification.

Open-source workflow makes spatial proteomics easier to use

Fabian Coscia and his team have published in Nature Methods an open-source workflow that makes Deep Visual Proteomics easier to use, adapt and scale. OpenDVP enables scientists to spatially map thousands of proteins inside ...