Immunology is the scientific discipline that investigates the molecular, cellular, and systemic mechanisms underlying immune recognition, regulation, and effector function in vertebrates and other organisms. It encompasses the study of innate and adaptive immune responses, including antigen processing and presentation, clonal selection, tolerance, immune memory, and the cytokine networks that orchestrate these processes. Immunology also examines the pathophysiology of immune-mediated diseases such as autoimmunity, allergy, immunodeficiencies, and transplant rejection, and underpins the rational design of vaccines, monoclonal antibodies, immunotherapies, and diagnostic assays through quantitative, genetic, and systems-level approaches.
The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical trial stages, the first COVID-19 mRNA vaccine was administered on 8 December 2020 and mathematical models ...
Bio & Medicine
Mar 11, 2026
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Johns Hopkins Medicine scientists say they have developed a simplified version of biodegradable nanoparticles that can "educate" the immune system to find and destroy disease-causing cells throughout the body. The study, ...
Bio & Medicine
Mar 11, 2026
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A Purdue University contraceptive vaccine seeks to address animal overpopulation by markedly reducing fertility in feral horses, deer, swine and other animals. Dr. Harm HogenEsch, distinguished professor of immunopathology ...
Molecular & Computational biology
Mar 8, 2026
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24
Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the production of interferons, which ...
Cell & Microbiology
Mar 6, 2026
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61
Research on preventing type 1 diabetes often focuses on limiting the autoimmune response that destroys the body's ability to produce its own insulin. A new technology developed by scientists at the University of Chicago takes ...
Bio & Medicine
Mar 1, 2026
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84
A study reveals how two proteins cooperate in a key early step of antiviral detection, as reported by researchers at Science Tokyo. Using cryo-electron microscopy and high-speed atomic force microscopy, they found that LGP2 ...
Cell & Microbiology
Feb 27, 2026
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Over the years, cell biology has built a detailed picture of how cells compartmentalize their internal functions. Central to this organization is the nucleus, which houses the genetic material and is separated from the cytoplasm ...
Cell & Microbiology
Feb 25, 2026
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Canine cancer patients receiving a new form of immunotherapy lived longer or shorter depending on the composition of their microbiome, the community of organisms living in their gut. Results of the clinical trial led by Oregon ...
Cell & Microbiology
Feb 17, 2026
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What if cattle were selected not only for their productivity, but also for their resistance to disease? A study conducted by a team of scientists combining systemic immunology, genomics and machine learning provides a better ...
Molecular & Computational biology
Feb 11, 2026
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20
University of Toronto researchers have expanded our understanding of bacterial immunity with the discovery of a new protein that can both sense and counteract viral infections. In the study, published in Nature, researchers ...
Cell & Microbiology
Feb 4, 2026
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