Host-pathogen interactions are the dynamic, reciprocal biological processes that occur between a host organism and an invading pathogen, encompassing molecular recognition, immune sensing, signaling, and effector responses, as well as pathogen strategies for attachment, invasion, replication, and immune evasion. These interactions involve pattern recognition receptors (e.g., Toll-like, NOD-like, and RIG-I-like receptors), pathogen-associated molecular patterns, and downstream signaling pathways that regulate inflammation, cell death, and antimicrobial defenses. Concurrently, pathogens deploy virulence factors, secretion systems, and immune-modulatory molecules to manipulate host cell pathways, subvert immunity, and optimize their survival, replication, and transmission, thereby determining infection outcomes and disease pathogenesis.
Decades of research has shown promise for using microbiome science to solve several problems facing agriculture, but these findings have not yet been translated to practical recommendations for growers, according to a team ...
Cell & Microbiology
Feb 28, 2026
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44
The Microbiology Society's Microbiology Outlooks, launched in 2025, has published its inaugural article: "When Theory Meets Genomics: Reconciling Game Dynamics and Within-Host Evolution." The new commentary explores how theoretical ...
Cell & Microbiology
Feb 28, 2026
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22
Our bodies are home to millions of fungi that, for the most part, are completely harmless. However, they can sometimes change from peaceful residents into dangerous invaders. One such is Candida parapsilosis, which normally ...
How do evolutionarily conserved pathogen effectors maintain structural stability while engaging diverse host targets? In a new study published in Molecular Plant Microbe Interactions, researchers at the University of Pretoria's ...
Plants & Animals
Feb 25, 2026
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12
Plants have an immune system, like people, and when it is triggered by threats like disease or pests, a plant's defenses are activated. But there's a downside to this protective mechanism: the plant's growth is suppressed ...
Biotechnology
Feb 23, 2026
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29
What do coffee, sugar, wheat, soy, eucalypts and paperbarks all have in common?
Plants & Animals
Feb 23, 2026
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16
Herpes simplex virus type 1 (HSV-1) infection dramatically remodels the host cell's nuclear structures. Infection leads to the formation of viral replication compartments and to chromatin marginalization to the nuclear periphery. ...
Cell & Microbiology
Feb 22, 2026
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21
Scientists have uncovered an elegant biophysical trick that tuberculosis-causing bacteria use to survive inside human cells, a discovery that could lead to new strategies for fighting one of the world's deadliest infectious ...
Cell & Microbiology
Feb 21, 2026
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103
In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma that viruses lack protein ...
For anyone who relies on coffee to start their day, coffee wilt disease may be the most important disease you've never heard of. This fungal disease has repeatedly reshaped the global coffee supply over the past century, ...
Molecular & Computational biology
Feb 18, 2026
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