Page 7: Research news on Host-Pathogen Interactions

Host-pathogen interactions are the dynamic, reciprocal biological processes that occur between a host organism and an invading pathogen, encompassing molecular recognition, immune sensing, signaling, and effector responses, as well as pathogen strategies for attachment, invasion, replication, and immune evasion. These interactions involve pattern recognition receptors (e.g., Toll-like, NOD-like, and RIG-I-like receptors), pathogen-associated molecular patterns, and downstream signaling pathways that regulate inflammation, cell death, and antimicrobial defenses. Concurrently, pathogens deploy virulence factors, secretion systems, and immune-modulatory molecules to manipulate host cell pathways, subvert immunity, and optimize their survival, replication, and transmission, thereby determining infection outcomes and disease pathogenesis.

A new strategy can improve safety in poultry processing

Salmonella is a common source of food poisoning that leads to potentially life-threatening illnesses, widespread food recalls and a consistent challenge for poultry producers. UConn Department of Animal Science associate ...

Mapping cotton bacterial blight resistance

Spoorti Gandhadmath carefully placed 3.5-inch (8.9-centimeter) pots on a shelf in a growth chamber. Within seven days of sowing, newly sprouted leaves had fully emerged from each of the carefully selected seeds, representing ...

The giant viruses that orchestrate life in the polar regions

Viruses play a major role in the functioning of ecosystems. They profoundly influence the dynamics of microbial communities, the flow of matter and global biogeochemical cycles. Yet despite their abundance and ecological ...

How H5N1 bird flu hid unrecognized for weeks in dairy cattle

When H5N1 bird flu first began infecting U.S. cattle in early 2024, diagnosis was elusive because, in cows, the disease looked completely different. Instead of affecting the lungs, as H5N1 does in other mammalian species, ...

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