Host-pathogen interactions are the dynamic, reciprocal biological processes that occur between a host organism and an invading pathogen, encompassing molecular recognition, immune sensing, signaling, and effector responses, as well as pathogen strategies for attachment, invasion, replication, and immune evasion. These interactions involve pattern recognition receptors (e.g., Toll-like, NOD-like, and RIG-I-like receptors), pathogen-associated molecular patterns, and downstream signaling pathways that regulate inflammation, cell death, and antimicrobial defenses. Concurrently, pathogens deploy virulence factors, secretion systems, and immune-modulatory molecules to manipulate host cell pathways, subvert immunity, and optimize their survival, replication, and transmission, thereby determining infection outcomes and disease pathogenesis.
Research at the University of Jyväskylä (Finland) reveals that autonomous parvoviruses, such as canine parvovirus, are highly capable of affecting the internal balance of the nucleolus. The results provide new basic information ...
Cell & Microbiology
Feb 11, 2026
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13
New research on avian malaria, which has decimated Hawaii's beloved birds, explains how non-native birds play a key role in transmission and contribute to the widespread distribution of the disease. This disease threatens ...
Ecology
Feb 10, 2026
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20
Researchers at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have developed a new inhalable form of tuberculosis (TB) treatment that could significantly reduce the burden of current therapy. ...
Bio & Medicine
Feb 10, 2026
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26
Rivals or allies—how do bacteria and fungi interact in our bodies? Until now, bacteria on our mucous membranes were primarily considered to be antagonists of fungi, as they can inhibit their growth. However, an international ...
Ecology
Feb 6, 2026
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256
Plants are a rich and renewable source of compounds used in medicines, food ingredients, and cosmetics. Since growing an entire plant just to extract a few specific compounds is rather inefficient, scientists are turning ...
Cell & Microbiology
Feb 4, 2026
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21
University of Toronto researchers have expanded our understanding of bacterial immunity with the discovery of a new protein that can both sense and counteract viral infections. In the study, published in Nature, researchers ...
Cell & Microbiology
Feb 4, 2026
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24
Australian researchers have developed a powerful new way to target deadly, drug-resistant bacteria by designing antibodies that recognize a sugar found only on bacterial cells—an advance that could underpin a new generation ...
Molecular & Computational biology
Feb 4, 2026
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60
Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and bind to receptors on the surface of target cells, a molecular arms race that drives constant evolution. ...
Evolution
Feb 2, 2026
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21
A debilitating hoof disease affecting elk herds across the Pacific Northwest appears to be driven not by a single pathogen but by multiple bacterial species working together, according to a study led by researchers in Washington ...
Plants & Animals
Feb 2, 2026
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18
Pneumocystis is an unwieldy genus of fungal pathogens that cause severe pneumonia, particularly in immunocompromised people like those with HIV/AIDs or who have received organ transplants. However, the mechanisms by which ...
Cell & Microbiology
Jan 28, 2026
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