Host-pathogen interactions are the dynamic, reciprocal biological processes that occur between a host organism and an invading pathogen, encompassing molecular recognition, immune sensing, signaling, and effector responses, as well as pathogen strategies for attachment, invasion, replication, and immune evasion. These interactions involve pattern recognition receptors (e.g., Toll-like, NOD-like, and RIG-I-like receptors), pathogen-associated molecular patterns, and downstream signaling pathways that regulate inflammation, cell death, and antimicrobial defenses. Concurrently, pathogens deploy virulence factors, secretion systems, and immune-modulatory molecules to manipulate host cell pathways, subvert immunity, and optimize their survival, replication, and transmission, thereby determining infection outcomes and disease pathogenesis.
The mystery of why some amphibian populations recover following outbreaks of a deadly fungus has been solved in a new study led by University College London (UCL), ZSL and Imperial College London.
Plants & Animals
8 hours ago
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10
Researchers have discovered that a group of viruses known to infect an agriculturally important plant pathogen has remained genetically stable for an astonishing four decades. The discovery of a disease-fighting virus that ...
Cell & Microbiology
Jul 13, 2026
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13
Tiny particles made from the membranes of human immune cells could offer a promising new way to fight fungal infections that are becoming harder to treat. Engineers at the University of California San Diego created antifungal ...
Bio & Medicine
Jul 11, 2026
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254
Northwestern Medicine scientists have identified a novel mechanism used by the bacteria responsible for gonorrhea to evade immune detection and achieve widespread infection, according to a recent study published in the Proceedings ...
Molecular & Computational biology
Jul 11, 2026
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10
To prevent viruses from sickening or killing us—whether it's an individual case of hepatitis B or a COVID pandemic—it's crucial to understand how the proteins they make initiate changes in our bodies that allow them to flourish. ...
Molecular & Computational biology
Jul 10, 2026
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7
Decaying matter shapes life in soil, but it can also create hostile zones for growing roots. Professor Jiří Friml of the Institute of Science and Technology Austria (ISTA) and international collaborators have now identified ...
Ecology
Jul 9, 2026
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27
A few years ago, Austin Wrenn noticed something unsettling in his strawberry greenhouses at Wrenn's Farm in Zebulon, North Carolina. He was one of the first growers in the state to experience losses from an unexpected, aggressive ...
Cell & Microbiology
Jul 3, 2026
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22
What does a hantavirus do inside its rodent hosts? How do these viruses move through animal populations? And how is it that they cause almost no apparent symptoms in rodents, yet can be nearly fatal in humans? Specially Appointed ...
Plants & Animals
Jul 2, 2026
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26
Researchers at National Institute of Advanced Industrial Science and Technology (AIST), in collaboration with researchers from The University of Electro-Communications (UEC) and Akita Prefectural University, have discovered ...
Cell & Microbiology
Jul 2, 2026
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11
Millions of women worldwide suffer from vaginal yeast infections. These infections are most commonly caused by the fungus Candida albicans and can lead to symptoms ranging from itching and burning to recurrent inflammation. ...
Cell & Microbiology
Jul 1, 2026
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