Host-pathogen interactions are the dynamic, reciprocal biological processes that occur between a host organism and an invading pathogen, encompassing molecular recognition, immune sensing, signaling, and effector responses, as well as pathogen strategies for attachment, invasion, replication, and immune evasion. These interactions involve pattern recognition receptors (e.g., Toll-like, NOD-like, and RIG-I-like receptors), pathogen-associated molecular patterns, and downstream signaling pathways that regulate inflammation, cell death, and antimicrobial defenses. Concurrently, pathogens deploy virulence factors, secretion systems, and immune-modulatory molecules to manipulate host cell pathways, subvert immunity, and optimize their survival, replication, and transmission, thereby determining infection outcomes and disease pathogenesis.
Bats are reservoirs for several zoonotic viruses, such as Ebola and coronaviruses. These pathogens can spread to humans through direct contact with the flying mammals or their bodily fluids, or indirectly through contaminated ...
Researchers at the University of Michigan have revealed that cells use a previously unknown feat of molecular craftsmanship to help protect their larger host organisms. The building blocks required for this work are found ...
Cell & Microbiology
Mar 12, 2026
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An international team of researchers has modified a probiotic yeast to make it safer for use by immunocompromised people, older adults and infants. Testing in an animal model found that the modified yeast is less likely to ...
Cell & Microbiology
Mar 9, 2026
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Long before humans cultivated crops or sailed between continents, a group of plant viruses was already evolving among wild plants in Eurasia. According to a new international study published in Plant Disease, the ancestors ...
Evolution
Mar 9, 2026
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Orthohantaviruses, such as the Puumala virus, are widespread in Europe, causing flu-like illnesses and severe kidney damage in those infected. It is increasingly considered a zoonotic threat. Researchers from the Medical ...
Cell & Microbiology
Mar 9, 2026
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Soybean cyst nematode (SCN) is among the most damaging pests affecting soybean crops around the world, with current management strategies relying primarily on a very narrow set of resistant soybean varieties, along with crop ...
Cell & Microbiology
Mar 5, 2026
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The cold season is in full swing, throats are scratchy and noses are running. We feel ill and hope it is not the flu. The influenza virus continues to pose a threat to our health. It triggers seasonal epidemics and, from ...
Cell & Microbiology
Mar 4, 2026
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For the first time, research shows that a key social trait in honey bees is linked to measurable physiological advantages that can improve colony survival. A study published in PLOS One uncovers how hygienic honey bee colonies ...
Plants & Animals
Mar 4, 2026
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Decades of research has shown promise for using microbiome science to solve several problems facing agriculture, but these findings have not yet been translated to practical recommendations for growers, according to a team ...
Cell & Microbiology
Feb 28, 2026
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The Microbiology Society's Microbiology Outlooks, launched in 2025, has published its inaugural article: "When Theory Meets Genomics: Reconciling Game Dynamics and Within-Host Evolution." The new commentary explores how theoretical ...
Cell & Microbiology
Feb 28, 2026
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