Research news on Host-Parasite Interactions

Host-parasite interactions are dynamic biological processes encompassing the molecular, cellular, physiological, and ecological exchanges between a parasite and its host that determine infection establishment, persistence, and transmission. They include mechanisms of host recognition and invasion, nutrient acquisition, immune evasion and modulation by the parasite, and host immune detection, effector responses, and tolerance strategies. These interactions drive coevolutionary arms races, shaping parasite virulence, host resistance, and specificity through genetic variation and selection. At the systems level, host-parasite interactions influence pathogen life cycles, tissue tropism, and disease outcomes, integrating signaling pathways, microbiome context, and environmental factors that modulate susceptibility and epidemiological patterns.

How methylation sets a parasite in motion to invade host cells

Parasites such as Toxoplasma gondii and the malaria parasite Plasmodium falciparum depend on rapid, precisely controlled movement to complete their life cycles. To start moving, they must assemble actin filaments at their ...

Chagas parasite's survival trick offers antimalarial-style target

Researchers at the University of Cincinnati have identified a potential new target to prevent the spread of Chagas disease. The parasitic infection is transmitted through the bite of the kissing bug in Central and South America ...

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