Page 11: Research news on Genomes

Genomes, as physical systems, comprise the complete set of nucleic acid molecules (typically DNA, or RNA in some viruses) that encode the hereditary information of an organism, including all chromosomes and extrachromosomal genetic elements. They are organized into linear or circular polymers of nucleotides, with specific higher-order structures such as chromatin in eukaryotes or nucleoid organization in prokaryotes. At the physical level, genomes exhibit defined sequence composition, length, and structural features (e.g., replication origins, regulatory regions, repetitive elements) that collectively determine their stability, replication dynamics, mutational patterns, and interactions with cellular molecular machinery.

Why are sloths slow? It's in their DNA

Sloths are the slowest mammals on the planet, but living in dense jungles has made them notoriously difficult to study. For the first time, scientists have now sequenced and analyzed the two-toed sloth genome and revealed ...

Why does the Y chromosome retain UTY?

A study, published in the journal Development, is the first to precisely map endogenous UTY occupancy across the human genome and demonstrate that UTY remains functionally involved in transcriptional regulation during early ...

Overlooked DNA structures help organize the genome

Northwestern Medicine scientists have discovered that little-studied DNA structures play a central role in organizing the human genome and controlling gene activity, according to a new study published in the Proceedings of ...

Scientists unveil ten-year roadmap for building synthetic cells

Scientists from six Asian countries have launched an ambitious 10-year effort to build synthetic cells from non-living molecules, marking the region's first coordinated push to create an artificial single-celled biological ...

The Y chromosome is home to surprising jumping genes

The humble Y chromosome may be the smallest chromosome in the mammalian genome (and getting even smaller), but it is mighty: Genes on the Y chromosome are critical for fertility in males. In a new study in the journal Current ...

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