Genetically engineered organisms (GEOs) are biological entities—prokaryotic or eukaryotic—whose genomes have been deliberately modified using recombinant DNA technologies, genome editing tools (e.g., CRISPR-Cas systems, TALENs, ZFNs), or transgenic methods to introduce, delete, or alter specific genetic sequences. This topic encompasses the design, construction, and characterization of modified genomes; vector systems and delivery methods; control of gene expression; and assessment of phenotypic consequences, stability, and off-target effects. It also includes applications in basic research, biotechnology, agriculture, biopharmaceutical production, and synthetic biology, as well as associated biosafety, containment, and regulatory frameworks governing experimental and environmental use.
Liver cells are indispensable for research—for drug testing, to better understand diseases such as hepatitis, fatty liver, cirrhosis, or liver cancer and for development of future cell therapies. However, obtaining human ...
Cell & Microbiology
Oct 29, 2025
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Researchers at Rice University have engineered living cells to use a 21st amino acid that illuminates protein changes in real time, providing a new method for observing changes within cells. The technique is effective in ...
Cell & Microbiology
Oct 23, 2025
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38
A single "sexy" gene could help us combat one of the world's most destructive fruit pests. By deleting the gene that lets female moths produce their mating scent, colleagues and I created an "unsexy" moth—and showed one way ...
Plants & Animals
Oct 15, 2025
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For decades, synthetic biologists have been developing gene circuits that can be transferred into cells for applications such as reprogramming a stem cell into a neuron or generating a protein that could help treat a disease ...
Biotechnology
Oct 13, 2025
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University of Warwick research demonstrates how to engineer "cell factories" that last longer and produce more chemicals, without needing antibiotics or complex engineering methods, paving the way for sustainable biotech ...
Biotechnology
Sep 30, 2025
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An international workshop of scientists, regulators, and industry experts led by Prof Ivana Barbaric convened to address the risks of genetic mutations in stem cell therapy.
Cell & Microbiology
Sep 30, 2025
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23
Natural systems such as CRISPR-associated transposons (CASTs) offer a targetable, one-step way to edit genomes. However, adapting them for biomedical applications has been challenging.
Biotechnology
Sep 24, 2025
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In a development that could help protect one of the world's most beloved agricultural commodities, a research team at Penn State has successfully created disease-resistant cacao plants using gene-editing technology. According ...
Molecular & Computational biology
Sep 24, 2025
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Corn rootworms, pests responsible for billions of dollars in yearly crop losses, are evolving resistance that weakens even the latest biotechnology controls, according to a new study published in the journal Proceedings of ...
Biotechnology
Sep 23, 2025
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123
Every year, millions of poinsettias brighten up windowsills around the world. But behind the festive plant lies a hidden problem: the beautiful branching, which gives the poinsettia its decorative shape, is caused by a bacterial ...
Plants & Animals
Sep 22, 2025
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