Page 8: Research news on genetically engineered organisms

Genetically engineered organisms (GEOs) are biological entities—prokaryotic or eukaryotic—whose genomes have been deliberately modified using recombinant DNA technologies, genome editing tools (e.g., CRISPR-Cas systems, TALENs, ZFNs), or transgenic methods to introduce, delete, or alter specific genetic sequences. This topic encompasses the design, construction, and characterization of modified genomes; vector systems and delivery methods; control of gene expression; and assessment of phenotypic consequences, stability, and off-target effects. It also includes applications in basic research, biotechnology, agriculture, biopharmaceutical production, and synthetic biology, as well as associated biosafety, containment, and regulatory frameworks governing experimental and environmental use.

Glowing amino acid sensors track cellular changes as they happen

Researchers at Rice University have engineered living cells to use a 21st amino acid that illuminates protein changes in real time, providing a new method for observing changes within cells. The technique is effective in ...

A new system can dial expression of synthetic genes up or down

For decades, synthetic biologists have been developing gene circuits that can be transferred into cells for applications such as reprogramming a stem cell into a neuron or generating a protein that could help treat a disease ...

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