Genetically engineered organisms (GEOs) are biological entities—prokaryotic or eukaryotic—whose genomes have been deliberately modified using recombinant DNA technologies, genome editing tools (e.g., CRISPR-Cas systems, TALENs, ZFNs), or transgenic methods to introduce, delete, or alter specific genetic sequences. This topic encompasses the design, construction, and characterization of modified genomes; vector systems and delivery methods; control of gene expression; and assessment of phenotypic consequences, stability, and off-target effects. It also includes applications in basic research, biotechnology, agriculture, biopharmaceutical production, and synthetic biology, as well as associated biosafety, containment, and regulatory frameworks governing experimental and environmental use.
Metabolic engineering has enabled the construction of efficient microbial cell factories, but cellular aging and the accumulation of toxic metabolites during prolonged fed-batch fermentation induce metabolic stress, which ...
Cell & Microbiology
Nov 18, 2025
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20
Ecuadorian scientists are developing a biotechnological strategy to stop banana wilt by genetically editing the causative fungus. Global banana production—one of the pillars of food security and a key source of income for ...
Biotechnology
Nov 13, 2025
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183
Insects that feed on starch can find veritable feasts in corn, pea, and bean crops or warehouses. It is no coincidence that the ancestors of these commercial plants developed α-amylase inhibitor proteins, which make the starch ...
Biotechnology
Nov 12, 2025
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127
A team of researchers has found a way to turn the bacteria living in the digestive tracts of animals into factories that can produce compounds that promote longevity in their hosts—showing a potential new drug development ...
Cell & Microbiology
Nov 12, 2025
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186
A new study shows, for the first time, that cow cells can naturally become immortal—continuing to divide indefinitely without genetic modification or any abnormal transformation. This overturns long-held assumptions that ...
Biotechnology
Nov 12, 2025
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90
A team led by University of Pittsburgh's Graham Hatfull has developed a method to construct bacteriophages with entirely synthetic genetic material, allowing researchers to add and subtract genes at will. The findings open ...
Biotechnology
Nov 10, 2025
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120
As Earth's climate warms and changes, sustainable agricultural practices are critical for feeding a rapidly growing population. Can we genetically engineer crops to adapt to drought and other effects of a warming climate?
Biotechnology
Nov 10, 2025
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31
Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing the synthetic gene circuits ...
Cell & Microbiology
Nov 7, 2025
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32
Plant biologists have developed a method for growing transgenic and gene-edited plants that cuts the slow and expensive process down from months to weeks.
Biotechnology
Nov 6, 2025
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94
A research team led by Professor Wang Peng from the Hefei Institutes of Physical Science of the Chinese Academy of Sciences, together with international researchers, has successfully engineered liquid-liquid phase separation ...
Cell & Microbiology
Nov 5, 2025
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