Genetically engineered organisms (GEOs) are biological entities—prokaryotic or eukaryotic—whose genomes have been deliberately modified using recombinant DNA technologies, genome editing tools (e.g., CRISPR-Cas systems, TALENs, ZFNs), or transgenic methods to introduce, delete, or alter specific genetic sequences. This topic encompasses the design, construction, and characterization of modified genomes; vector systems and delivery methods; control of gene expression; and assessment of phenotypic consequences, stability, and off-target effects. It also includes applications in basic research, biotechnology, agriculture, biopharmaceutical production, and synthetic biology, as well as associated biosafety, containment, and regulatory frameworks governing experimental and environmental use.
Understanding human gene function in living organisms has long been hampered by fundamental differences between species. Although mice share most protein-coding genes with humans, their regulatory landscapes often diverge, ...
Biotechnology
Jan 17, 2026
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123
A research team led by Associate Professor Hirofumi Nishizono and graduate student Masaki Kato from the Research Support Center at the Medical Research Institute of Kanazawa Medical University has identified eleven novel ...
Cell & Microbiology
Jan 14, 2026
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13
Using ribosome engineering (RE), researchers from Shinshu University introduced mutations affecting the protein synthesis mechanism of probiotic Lacticaseibacillus rhamnosus GG (LGG). These mutant LGGs exhibit altered surface ...
Cell & Microbiology
Jan 7, 2026
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16
A collaborative team of researchers from the Donald Danforth Plant Science Center, the University of Florida, Gainesville and University of Iowa have developed tools that allow grasses—including major grain crops like corn—to ...
Biotechnology
Jan 6, 2026
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43
Like other developing countries, Indonesia is facing a familiar dilemma: how to feed a growing population while protecting its extraordinary biodiversity.
Biotechnology
Jan 5, 2026
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29
Agriculture, from the outset, has been made possible by humans tweaking the genes of plants to make them grow faster, produce more of what we want, and survive drought, pests, and infection. For millennia, we did it with ...
Biotechnology
Dec 18, 2025
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24
Researchers have developed a new "color-coded" genetic method that makes it easy to distinguish male and female mosquitoes. This innovation can help solve a major bottleneck in mosquito control strategies that rely on releasing ...
Biotechnology
Dec 17, 2025
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36
Researchers at the Icahn School of Medicine at Mount Sinai have developed a first-of-its-kind mRNA system that switches on therapeutic genes preferentially inside targeted cells—an advance demonstrated in studies in mice ...
Bio & Medicine
Dec 15, 2025
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190
Researchers have found a way to control protein levels inside different tissues of a whole, living animal for the first time. The method lets scientists dial protein levels up or down with great precision during the animal's ...
Biotechnology
Dec 12, 2025
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399
In a new study published in Nature, scientists have successfully developed genetically modified mosquitoes in Tanzania that block the transmission of malaria. The team includes researchers from the Ifakara Health Institute ...
Biotechnology
Dec 11, 2025
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