Genetically engineered organisms (GEOs) are biological entities—prokaryotic or eukaryotic—whose genomes have been deliberately modified using recombinant DNA technologies, genome editing tools (e.g., CRISPR-Cas systems, TALENs, ZFNs), or transgenic methods to introduce, delete, or alter specific genetic sequences. This topic encompasses the design, construction, and characterization of modified genomes; vector systems and delivery methods; control of gene expression; and assessment of phenotypic consequences, stability, and off-target effects. It also includes applications in basic research, biotechnology, agriculture, biopharmaceutical production, and synthetic biology, as well as associated biosafety, containment, and regulatory frameworks governing experimental and environmental use.
New drugs that target "zombie" tuberculosis (TB) cells are now a step closer, thanks to a new study led by the University of Surrey, published in Scientific Reports.
Cell & Microbiology
Jul 3, 2025
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36
By combining artificial intelligence with automated robotics and synthetic biology, researchers at the University of Illinois Urbana-Champaign have dramatically improved the performance of two important industrial enzymes—and ...
Biotechnology
Jul 1, 2025
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68
Plant scientists have used a standard "gene gun" since 1988 to genetically modify crops for better yield, nutrition, pest resistance and other valuable traits.
Plants & Animals
Jul 1, 2025
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59
Genome editing technologies like CRISPR-Cas9 have transformed biology, medicine, and agriculture, but concerns remain about unintended edits at off-target DNA sites. These off-target effects can cause harmful mutations and ...
Biotechnology
Jul 1, 2025
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24
A new gene therapy delivery device could let hospital pharmacies make personalized nanomedicines to order. This democratized approach to precision medicine, as published in Frontiers in Science, could revolutionize how hospitals ...
Bio & Medicine
Jun 26, 2025
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59
Researchers at DTU Biosustain (The Novo Nordisk Foundation Center for Biosustainability at DTU) have developed a new tool that significantly accelerates and simplifies the genetic engineering of yeast strains used in industrial ...
Cell & Microbiology
Jun 23, 2025
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45
While some scientists argue that agricultural gene editing regulations are overly restrictive, a new paper from the University of Adelaide emphasizes the importance of clear regulations to ensure that new technologies are ...
Molecular & Computational biology
Jun 23, 2025
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25
Researchers from the Lawrence Berkeley National Laboratory (Berkeley Lab), UC Irvine, and the University of Illinois Urbana-Champaign (UIUC), have used biology to convert human urine into a valuable product. The team genetically ...
Cell & Microbiology
Jun 17, 2025
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41
Genetic changes can occur naturally through evolution or can be initiated with the help of genetic engineering. The bacterium Thermoanaerobacter kivui (T. kivui) was manipulated by a research team led by Stefan Pflügl from ...
Cell & Microbiology
Jun 12, 2025
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28
Thanks to a clever modification of the baculovirus, vaccines can now be produced in insect cells more easily and cleaner. Researchers at Wageningen University & Research (WUR) have successfully developed vaccine material ...
Cell & Microbiology
Jun 10, 2025
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