Genetically engineered organisms (GEOs) are biological entities—prokaryotic or eukaryotic—whose genomes have been deliberately modified using recombinant DNA technologies, genome editing tools (e.g., CRISPR-Cas systems, TALENs, ZFNs), or transgenic methods to introduce, delete, or alter specific genetic sequences. This topic encompasses the design, construction, and characterization of modified genomes; vector systems and delivery methods; control of gene expression; and assessment of phenotypic consequences, stability, and off-target effects. It also includes applications in basic research, biotechnology, agriculture, biopharmaceutical production, and synthetic biology, as well as associated biosafety, containment, and regulatory frameworks governing experimental and environmental use.
Ancient events in plant evolution have left behind large, duplicated regions in their genomes. Salk Institute scientists found that deleting these large blocks of DNA can still lead to normal plants. The findings demonstrate ...
Plants & Animals
Aug 13, 2025
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87
Researchers have controlled the evolution of E. coli bacteria in the lab in order to dramatically increase the amount of plasmid DNA (pDNA) these modified bacteria produce. The advance is significant because pDNA is an essential—and ...
Cell & Microbiology
Aug 13, 2025
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28
A research team headed by the University of Zurich has developed a powerful new method to precisely edit DNA by combining cutting-edge genetic engineering with artificial intelligence. The work has been published in Nature ...
Biotechnology
Aug 12, 2025
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295
The FDA's approval of the first CRISPR-Cas9–based gene therapy marked a major milestone in biomedicine, validating genome editing as a promising treatment strategy for disorders like sickle cell disease, muscular dystrophy, ...
Biotechnology
Aug 7, 2025
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387
The targeted engineering of artificial proteins with unique properties is now possible with the assistance of a novel method developed by a research team led by Prof. Dr. Dominik Niopek at the Institute of Pharmacy and Molecular ...
Biotechnology
Aug 5, 2025
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29
The DNA of nearly all life on Earth contains many redundancies, and scientists have long wondered whether these redundancies served a purpose or if they were just leftovers from evolutionary processes. Both DNA and RNA contain ...
Texas A&M AgriLife Research has reached a major milestone in increasing the value of cotton, marking the initial step toward commercial adoption of food-ingredient cottonseed. This innovative development was led by Keerti ...
Agriculture
Aug 1, 2025
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28
Researchers at Rice University have engineered E. coli to act as living multiplexed sensors, allowing these genetically modified cells to detect and respond to multiple environmental toxins simultaneously by converting their ...
Biotechnology
Jul 29, 2025
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48
In a major step toward securing global food supplies and advancing sustainable agriculture, a team of scientists has proposed an integrated framework that combines biotechnology and artificial intelligence (AI) to revolutionize ...
Biotechnology
Jul 23, 2025
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44
Mosquitoes kill more people each year than any other animal. In 2023, the blood-sucking insects infected a reported 263 million people with malaria, leading to nearly 600,000 deaths, 80% of which were children.
Plants & Animals
Jul 23, 2025
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36
