Genetically engineered organisms (GEOs) are biological entities—prokaryotic or eukaryotic—whose genomes have been deliberately modified using recombinant DNA technologies, genome editing tools (e.g., CRISPR-Cas systems, TALENs, ZFNs), or transgenic methods to introduce, delete, or alter specific genetic sequences. This topic encompasses the design, construction, and characterization of modified genomes; vector systems and delivery methods; control of gene expression; and assessment of phenotypic consequences, stability, and off-target effects. It also includes applications in basic research, biotechnology, agriculture, biopharmaceutical production, and synthetic biology, as well as associated biosafety, containment, and regulatory frameworks governing experimental and environmental use.
An international team of researchers has achieved a breakthrough in the production of doxorubicin, a vital chemotherapy agent. The study identifies and resolves molecular "bottlenecks" that have limited the natural production ...
Biotechnology
Mar 13, 2026
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An interdisciplinary research team from two working groups at the Center for Synthetic Biology at TU Darmstadt has developed the first RNA-based genetic switch that precisely replicates the logical behavior of a NAND gate, ...
Biotechnology
Mar 11, 2026
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An international team of researchers has modified a probiotic yeast to make it safer for use by immunocompromised people, older adults and infants. Testing in an animal model found that the modified yeast is less likely to ...
Cell & Microbiology
Mar 9, 2026
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A research team affiliated with UNIST has engineered a microbial strain capable of rapidly growing in high concentrations of methanol, marking a significant step forward in biorefinery technology. This breakthrough provides ...
Cell & Microbiology
Mar 6, 2026
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Protein activity can be precisely regulated via subtle changes in temperature using heat-sensitive switches. Underlying this capability is a novel modular design strategy developed by researchers at the Institute of Pharmacy ...
Biotechnology
Mar 5, 2026
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The DNA foundation model Evo 2 has been published in the journal Nature. Trained on the DNA of over 100,000 species across the entire tree of life, Evo 2 can identify patterns in gene sequences across disparate organisms ...
Biotechnology
Mar 4, 2026
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In most plants and animals, including humans, mitochondria are inherited exclusively, or nearly exclusively, from the mother. By contrast, paternal transmission is observed only occasionally, and the mechanisms behind this ...
Plants & Animals
Mar 3, 2026
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Researchers at the Department of Chemical Engineering and Biotechnology (CEB) have found a new way to organize molecules inside living cells, opening possibilities for more controlled and efficient biomanufacturing. The team ...
Bio & Medicine
Feb 24, 2026
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A research team led by the University of Waterloo is developing a novel tool to treat cancer by engineering hungry bacteria to literally eat tumors from the inside out. "Bacteria spores enter the tumor, finding an environment ...
Cell & Microbiology
Feb 24, 2026
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Natural muscle fibers are made up of spring-like proteins that can contract and stretch without losing their original form, dissipate mechanical energy as heat and maintain incredible tensile strength for all sorts of physical ...
Biotechnology
Feb 23, 2026
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