Research news on Gastrointestinal Microbiome

The gastrointestinal microbiome as a biological process encompasses the dynamic interactions, succession, and functional activities of microbial communities residing along the digestive tract and their continuous crosstalk with the host. It involves microbial colonization, competition, and cooperation; fermentation of dietary substrates; synthesis and biotransformation of metabolites such as short-chain fatty acids and bile acid derivatives; modulation of epithelial barrier integrity; and regulation of local and systemic immune responses. This process is characterized by context-dependent compositional shifts (e.g., in response to diet, xenobiotics, and inflammation) that influence host metabolism, signaling pathways, and susceptibility to gastrointestinal and extraintestinal diseases.

Second ribosome binding site helps explain how tetracyclines work

For decades, doctors have widely used tetracyclines for conditions ranging from acne to tick-borne illnesses. Using high-resolution imaging technology, researchers in the laboratory of Christopher Bunick, MD, Ph.D., associate ...

Wine's leftovers could help wean chicken farms off antibiotics

Every year, millions of gallons of wine are pressed, leaving behind a mountain of pulpy residue—grape skins, seeds, stems and peels—that wineries struggle to dispose of. Now, researchers say this overlooked byproduct could ...

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