Research news on Gastrointestinal Microbiome

The gastrointestinal microbiome as a biological process encompasses the dynamic interactions, succession, and functional activities of microbial communities residing along the digestive tract and their continuous crosstalk with the host. It involves microbial colonization, competition, and cooperation; fermentation of dietary substrates; synthesis and biotransformation of metabolites such as short-chain fatty acids and bile acid derivatives; modulation of epithelial barrier integrity; and regulation of local and systemic immune responses. This process is characterized by context-dependent compositional shifts (e.g., in response to diet, xenobiotics, and inflammation) that influence host metabolism, signaling pathways, and susceptibility to gastrointestinal and extraintestinal diseases.

Bacteria from bumblebees can produce vitamin B₂ in soya drinks

Researchers at DTU have developed a new method that can reduce the time needed to find new bacteria for fermentation. They have now identified a bacterium that can be used both for acidification and to increase the vitamin ...

One of cholera's great enemies is found in the human gut

Cholera-causing bacteria are locked in an evolutionary arms race with a viral nemesis, according to a new genomic study. Researchers have found that, in the Ganges Delta, cholera bacteria rapidly gain and lose special armor ...

Gut bacteria may influence social behavior through smell

In a new study, Northwestern University neurobiologists discovered that gut bacteria and the nose work together to shape social behavior in mice, including who fights and who backs down. Using a combination of genetic and ...

Bacteria invent another way to turn on genes

In their landmark 1961 paper on the lac operon, Nobel laureates François Jacob and Jacques Monod speculated that RNA might control gene activity in bacteria through base-pairing interactions. But once protein transcription ...

Gut microbes: The secret to squirrel hibernation

When winter sets in and food becomes scarce, some mammals hibernate, entering a state of deep rest that slashes their energy needs and allows them to fast for months. However, fasting deprives them of essential nutrients, ...

How studying yeast in the gut could lead to new, better drugs

A new study sheds light on the behavior of yeast cells in the gut, paving the way for new lines of yeast that more efficiently produce therapeutic drugs tailored to address specific diseases. The research is published in ...

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