Flow cytometry is a high-throughput, laser-based analytical method used to quantify physical and biochemical characteristics of individual cells or particles suspended in fluid as they pass single-file through an interrogation point. Cells are typically labeled with fluorescent probes (e.g., antibody-conjugated fluorochromes) targeting specific surface or intracellular molecules. As each event traverses one or more laser beams, scattered light and fluorescence emissions are detected, converted to electronic signals, and analyzed to derive multiparametric data on cell size, granularity, phenotype, and functional states. The method underpins applications such as immunophenotyping, cell cycle and apoptosis analysis, minimal residual disease detection, and fluorescence-activated cell sorting (FACS) when coupled to sorting hardware.
Researchers from several Parisian institutions have worked together to develop a non-destructive approach to study how unicellular organisms respond to stress, focusing on cell-to-cell differences. Working together, the researchers ...
Biotechnology
Mar 24, 2026
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Cleaning blood from a violent crime scene can complicate crime scene investigations, particularly when accurate evidence is required for a conviction in court. A new study led by Flinders University, published in the Australian ...
Molecular & Computational biology
Feb 26, 2026
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Carbon dioxide (CO₂) connects us to the natural world: What we breathe out becomes fuel for forests. But inside our own bodies, CO₂ has a secret life. It sparks chemical reactions, shapes metabolism, and may even act as a ...
Cell & Microbiology
Feb 23, 2026
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14
In a 2023 paper on hypoxia and glucose metabolism, our lab showed how organisms rewire their metabolism to adapt to low oxygen levels—such as those found at high altitudes. One of the most striking observations from that ...
Cell & Microbiology
Feb 19, 2026
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70
A new study may change the way scientists think about the distance traveled by tiny bubbles carrying signals between cells that are embedded in tissue. These particles, called extracellular vesicles, are known to safely carry ...
Molecular & Computational biology
Feb 11, 2026
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10
Many advances in medicine and drug development were possible owing to flow cytometry, a single-cell analysis technique that analyzes cells using the emitted fluorescence of their chemical tags while passing through a laser ...
Cell & Microbiology
Sep 11, 2025
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19
Macrophages drive key immune processes including inflammation, tissue repair, and tumorigenesis via distinct polarization states whose accurate identification is vital for diagnosis and immunotherapy. However, methods like ...
Cell & Microbiology
Sep 10, 2025
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16
A team of researchers at the George R. Brown School of Engineering and Computing at Rice University has developed an innovative artificial intelligence (AI)-enabled, low-cost device that will make flow cytometry—a technique ...
Bio & Medicine
Feb 28, 2025
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78
The ability to detect diseases at an early stage or even predict their onset would be of tremendous benefit to doctors and patients alike. A research team led by Dr. Larysa Baraban at the Helmholtz-Zentrum Dresden-Rossendorf ...
Bio & Medicine
Feb 7, 2024
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134
A research team led by Prof. Chen Yan from the Shenzhen Institute of Advanced Technology (SIAT), Chinese Academy of Sciences, and their collaborators developed a novel digital droplet microfluidic flow cytometry technique, ...
Bio & Medicine
Aug 25, 2022
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