Page 7: Research news on developmental biology

Developmental biology is the branch of biological sciences that investigates the processes by which organisms grow, differentiate, and acquire their form from fertilization to adulthood and often through regeneration and aging. It integrates molecular genetics, cell biology, genomics, and systems biology to elucidate mechanisms such as cell fate specification, pattern formation, morphogenesis, and organogenesis. Developmental biology examines regulatory gene networks, signaling pathways (e.g., Wnt, Hedgehog, Notch, TGF-β), epigenetic modifications, and mechanical forces that coordinate spatial and temporal control of gene expression and cellular behavior, providing a framework for understanding congenital disorders, tissue regeneration, and evolutionary changes in body plans.

Why does the Y chromosome retain UTY?

A study, published in the journal Development, is the first to precisely map endogenous UTY occupancy across the human genome and demonstrate that UTY remains functionally involved in transcriptional regulation during early ...

'Genetic brakes' reveal how embryos shape their limbs

Canadian scientists have made a significant advance in understanding the mechanisms that enable embryos to properly form their limbs, thanks to new research led by Université de Montréal medical professor Marie Kmita at the ...

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