Page 5: Research news on Cellular organization, physiology & dynamics

Cellular organization, physiology & dynamics is a research area focused on understanding how cells are spatially structured, how their molecular components are functionally integrated, and how these features change over time and in response to internal and external cues. It encompasses the study of subcellular compartmentalization, cytoskeletal architecture, membrane trafficking, signal transduction, metabolic regulation, and cell-cycle control. Researchers in this field employ quantitative imaging, biophysical measurements, genetic perturbations, and computational modeling to link molecular interactions and mesoscale structures with emergent cellular behaviors, including motility, growth, differentiation, and responses to stress or pathological conditions.

Social amoebae form nanotube networks linking multiple cells

Social amoebae are unicellular organisms that act in concert, requiring extensive communication. Pierre Stallforth and colleagues studied modes of communication among cells of the social amoeba Dictyostelium discoideum, using ...

A lipid switch that blocks anthrax from entering cells

Every cell carefully builds and positions thousands of proteins that allow it to sense and respond to its surroundings. Even small changes to these proteins often determine whether they work properly or are destroyed before ...

Cracking the axolotl code: How to regrow limbs and stay young

Minor cuts and scrapes usually heal in time, but losing a finger or a whole limb? For most vertebrates, that's a done deal. Unless, of course, you've got the self-healing machinery of an axolotl.

Researchers uncover new mechanism behind DNA repair

Roughly 20 million people receive a cancer diagnosis each year, and an estimated 1 in 5 people will receive a cancer diagnosis in their lifetime. Cancer cells arise from damage to the cell's instruction manual: DNA.

Scientists pinpoint where cells first begin copying DNA

Researchers at the MRC Laboratory of Medical Sciences (LMS) and collaborators have uncovered one of the earliest steps in DNA replication: the moment a cell first opens its DNA to begin making a copy of its genome. The findings, ...

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