Cellular organization, physiology & dynamics is a research area focused on understanding how cells are spatially structured, how their molecular components are functionally integrated, and how these features change over time and in response to internal and external cues. It encompasses the study of subcellular compartmentalization, cytoskeletal architecture, membrane trafficking, signal transduction, metabolic regulation, and cell-cycle control. Researchers in this field employ quantitative imaging, biophysical measurements, genetic perturbations, and computational modeling to link molecular interactions and mesoscale structures with emergent cellular behaviors, including motility, growth, differentiation, and responses to stress or pathological conditions.
The membrane that encases a biological cell is not simply a barrier; it is chock full of proteins involved in all sorts of critical biological functions. To really understand what membrane proteins are doing and how, researchers ...
Bio & Medicine
Dec 21, 2023
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77
Some COVID-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy. ...
Bio & Medicine
Dec 11, 2023
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81
Researchers from Osaka University investigated the thermal energy changes across nanopores that allow the selective flow of ions. Switching off the flow of ions in one direction led to a cooling effect. The findings have ...
Nanophysics
Dec 11, 2023
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101
Enzyodynamic therapy (EDT) is a new type of reactive oxygen species (ROS)-related dynamic therapeutic modality, which adequately utilizes the enzyme-triggered catalytic reactions in living organisms and achieves disease treatment ...
Bio & Medicine
Oct 19, 2023
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119
A group of researchers at the Technical University of Munich (TUM) has developed the world's first microrobot ("microbot") capable of navigating within groups of cells and stimulating individual cells. Berna Özkale Edelmann, ...
Bio & Medicine
Sep 6, 2023
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177
Like loading dock managers at a shipping warehouse, nuclear pore complexes act as gatekeepers to the headquarters of the cell, controlling traffic out of the nucleus.
Bio & Medicine
Aug 25, 2023
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106
Led by Stefan Wilhelm, Ph.D., assistant professor in the Stephenson School of Biomedical Engineering at the University of Oklahoma, a team of researchers from the Gallogly College of Engineering at OU, OU Health Sciences ...
Bio & Medicine
May 9, 2023
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111
It's a big step forward in using extracellular vesicles (EVs) as a diagnostic tool. Lead study author, J. Nathaniel Diehl, Ph.D., at the UNC School of Medicine, led research showing how a new protocol in handling extracellular ...
Bio & Medicine
May 8, 2023
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134
The existing 3D-printed scaffolds commonly possess a thick feature size of hundreds of micrometers, which is too large for most cells (10–20 μm) to attach and proliferate for promoting tissue regeneration. Researchers from ...
Bio & Medicine
Mar 14, 2023
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145
Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and safe for use in humans, ...
Bio & Medicine
Mar 8, 2023
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121
