Page 33: Research news on Cellular organization, physiology & dynamics

Cellular organization, physiology & dynamics is a research area focused on understanding how cells are spatially structured, how their molecular components are functionally integrated, and how these features change over time and in response to internal and external cues. It encompasses the study of subcellular compartmentalization, cytoskeletal architecture, membrane trafficking, signal transduction, metabolic regulation, and cell-cycle control. Researchers in this field employ quantitative imaging, biophysical measurements, genetic perturbations, and computational modeling to link molecular interactions and mesoscale structures with emergent cellular behaviors, including motility, growth, differentiation, and responses to stress or pathological conditions.

A protein modification is critical for maintaining ER homeostasis

When improperly folded proteins build up in the endoplasmic reticulum (ER), cells become stressed and conditions such as type 2 diabetes, neurodegenerative disorders, and cancers can develop. In a recent study published in ...

Spatial transcriptomics guide emerges from analyzed samples

Technological development is key to improving the way hematologic cancer is diagnosed and treated. With this vision, the Josep Carreras Leukemia Research Institute is committed to the creation and implementation of new systems ...

What vibrating molecules might reveal about cell biology

Infrared vibrational spectroscopy at BESSY II can be used to create high-resolution maps of molecules inside live cells and cell organelles in their native aqueous environment, according to a new study by a team from HZB ...

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