Cellular organization, physiology & dynamics is a research area focused on understanding how cells are spatially structured, how their molecular components are functionally integrated, and how these features change over time and in response to internal and external cues. It encompasses the study of subcellular compartmentalization, cytoskeletal architecture, membrane trafficking, signal transduction, metabolic regulation, and cell-cycle control. Researchers in this field employ quantitative imaging, biophysical measurements, genetic perturbations, and computational modeling to link molecular interactions and mesoscale structures with emergent cellular behaviors, including motility, growth, differentiation, and responses to stress or pathological conditions.
Researchers at University of Tsukuba have achieved high-resolution visualization of cellular organelles, such as nuclei and mitochondria, using an external apodized phase contrast (ExAPC) microscope. By effectively suppressing ...
Cell & Microbiology
Nov 10, 2025
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22
Cell movement is an essential biological process, whether it's cancer cells metastasizing to other parts of the body or immune cells migrating to heal a wound. However, the principle by which cells autonomously determine ...
Cell & Microbiology
Nov 10, 2025
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22
For decades, scientists have known that motor proteins like kinesin-2 ferry vital cargo along microtubule "highways" inside cells. But how these molecular vehicles identify and bind to the right cargo remained a mystery. ...
Cell & Microbiology
Nov 6, 2025
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23
Scientists from Oxford's Radcliffe Department of Medicine have achieved the most detailed view yet of how DNA folds and functions inside living cells, revealing the physical structures that control when and how genes are ...
Cell & Microbiology
Nov 6, 2025
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74
Cardiovascular disease continues to be the leading cause of death worldwide. But advances in heart-failure therapeutics have stalled, largely due to the difficulty of delivering treatments at the cellular level. Now, a UC ...
Bio & Medicine
Nov 5, 2025
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117
Although heart cells and skin cells contain identical instructions for creating proteins encoded in their DNA, they're able to fill such disparate niches because molecular machinery can cut out and stitch together different ...
Biotechnology
Nov 4, 2025
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50
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial transcriptomics. Trained on ...
Cell & Microbiology
Nov 3, 2025
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28
A team of researchers at the University of Liverpool, working in collaboration with the Mechanobiology Institute at the National University of Singapore, has made a significant breakthrough in understanding how cells sense ...
Cell & Microbiology
Nov 3, 2025
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20
The design of new calcium channels, built bottom-up from scratch, was reported last week in Nature.
Biotechnology
Oct 29, 2025
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40
How do embryos develop? Why does the cortex of the mammalian brain fold? How do we feel touch at our fingertips? These and other fundamental biological questions remain unsolved. Yet, scientists know they all rely on a common ...
Cell & Microbiology
Oct 29, 2025
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