Page 27: Research news on Cellular organization, physiology & dynamics

Cellular organization, physiology & dynamics is a research area focused on understanding how cells are spatially structured, how their molecular components are functionally integrated, and how these features change over time and in response to internal and external cues. It encompasses the study of subcellular compartmentalization, cytoskeletal architecture, membrane trafficking, signal transduction, metabolic regulation, and cell-cycle control. Researchers in this field employ quantitative imaging, biophysical measurements, genetic perturbations, and computational modeling to link molecular interactions and mesoscale structures with emergent cellular behaviors, including motility, growth, differentiation, and responses to stress or pathological conditions.

Optogenetic screening platform for drug discovery introduced

A new study published in Cell has unveiled a first-of-a-kind optogenetic screening platform, developed by scientists at Integrated Biosciences, a biotechnology company integrating optogenetics, chemistry and AI to discover ...

A molecular switch packs DNA on time for cell division

If measured from beginning to end, the DNA in our cells is too long to fit into the cell's nucleus, explaining why it must be constantly folded and packaged. When it is time for cell division, and the genetic information ...

Research teases apart competing transcription organization models

Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying transcription, the process of converting genetic information in DNA into messenger RNA. Phase separation ...

Light-activated molecular cages reveal RNA locations in cells

A new tool called PHOTON, developed by scientists at UT Southwestern Medical Center, can identify RNA molecules at their native locations within cells—providing valuable clues to where different RNA species are distributed ...

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