Page 20: Research news on Cellular organization, physiology & dynamics

Cellular organization, physiology & dynamics is a research area focused on understanding how cells are spatially structured, how their molecular components are functionally integrated, and how these features change over time and in response to internal and external cues. It encompasses the study of subcellular compartmentalization, cytoskeletal architecture, membrane trafficking, signal transduction, metabolic regulation, and cell-cycle control. Researchers in this field employ quantitative imaging, biophysical measurements, genetic perturbations, and computational modeling to link molecular interactions and mesoscale structures with emergent cellular behaviors, including motility, growth, differentiation, and responses to stress or pathological conditions.

Tech upgrade reveals even finer transcription detail inside cells

In 2021, a technology developed at the University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity within intact tissue at microscopic resolution, enabling researchers to measure all expressed ...

Study identifies aging-associated mitochondrial circular RNAs

New research profiles mitochondrial circular RNAs in Peripheral Blood Mononuclear Cells (PBMCs) from young and old human cohorts and probes how mitochondrial circRNAs and the mitochondrial RNA-binding protein GRSF1 relate ...

Cellular switch casts light on why humans are active in the day

Early mammalian ancestors were nocturnal, sleeping during the day while the dinosaurs dominated the land. However, some mammalian lineages, including human ancestors, independently transitioned to diurnality (active during ...

How RNA binding selectivity arises from disordered regions

RIKEN researchers have discovered how an enzyme modifies gene expression by targeting certain stretches of messenger RNA (mRNA) while leaving others alone. This finding could contribute to the rational design of drugs that ...

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