Page 12: Research news on Cellular organization, physiology & dynamics

Cellular organization, physiology & dynamics is a research area focused on understanding how cells are spatially structured, how their molecular components are functionally integrated, and how these features change over time and in response to internal and external cues. It encompasses the study of subcellular compartmentalization, cytoskeletal architecture, membrane trafficking, signal transduction, metabolic regulation, and cell-cycle control. Researchers in this field employ quantitative imaging, biophysical measurements, genetic perturbations, and computational modeling to link molecular interactions and mesoscale structures with emergent cellular behaviors, including motility, growth, differentiation, and responses to stress or pathological conditions.

Exposing a hidden anchor for HIV replication

The tiny shell protecting the HIV virus resembles a slightly rounded ice cream cone, but there is nothing sweet about it. More than 40 million people worldwide live with AIDS because of this virus, and treatments must continually ...

Does the motion of DNA influence its activity?

How does our DNA store the massive amount of information needed to build a human being? And what happens when it's stored incorrectly? Jesse Dixon, MD, Ph.D., has spent years studying the way this genome is folded in 3D space—knowing ...

A yeast enzyme helps human cells overcome mitochondrial defects

Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most animal cells, this process depends closely on properly functioning mitochondria, the organelles ...

Parvovirus infection modulates nucleolar organization and function

Research at the University of Jyväskylä (Finland) reveals that autonomous parvoviruses, such as canine parvovirus, are highly capable of affecting the internal balance of the nucleolus. The results provide new basic information ...

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