Biomolecules, as physical systems, are distinct molecular entities synthesized or utilized by living organisms that exhibit specific structural, thermodynamic, and dynamical properties enabling biological function. They include nucleic acids, proteins, lipids, carbohydrates, and diverse metabolites, each characterized by defined covalent connectivity, three-dimensional conformations, and interaction potentials with solvents, ions, and other biomolecules. Their behavior is governed by quantum-mechanical bonding, classical electrostatics, and statistical thermodynamics, leading to emergent phenomena such as self-assembly, allostery, enzyme catalysis, and molecular recognition. In physical systems research, biomolecules are studied through techniques like spectroscopy, crystallography, cryo-EM, and molecular simulations to elucidate structure–function relationships and energy landscapes.
New research by an interdisciplinary team in Lithuania has revealed a promising and unconventional approach to cartilage regeneration. Using extracellular vesicles derived from menstrual blood stromal cells, the researchers ...
Bio & Medicine
Apr 10, 2026
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In December, The Conversation hosted a webinar on AI's revolutionary role in drug discovery and development. Science and technology editor Eric Smalley interviewed Jeffrey Skolnick, eminent scholar in computational systems ...
Molecular & Computational biology
Apr 7, 2026
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Researchers at Umeå University have contributed new insights into how cancer cells protect themselves from cell death. The study provides a deeper understanding of how key proteins interact within the cell and could, in the ...
Cell & Microbiology
Apr 7, 2026
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45
Ligand Pro, founded by Skoltech professors and a Skoltech Ph.D. student, has presented Matcha, an AI-powered molecular docking model that performs virtual drug screening 30 times faster than the large co-folding models of ...
Biotechnology
Apr 7, 2026
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How can cancer cells be targeted without damaging healthy tissue? This is one of the major challenges facing oncology today. Using synthetic DNA strands, a team from the University of Geneva (UNIGE) has created a "smart" ...
Bio & Medicine
Apr 1, 2026
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The integrity of DNA and RNA is essential for every cell. DNA contains the genetic information for proteins, while RNA serves as a working copy of individual genes and is required for the synthesis of proteins. Unlike DNA ...
Cell & Microbiology
Mar 30, 2026
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9
Proteins are far more than nutrients we track on a food label. Present in every cell of our bodies, they work like nature's molecular machines. They walk, stretch, bend, and flex to do their jobs, pumping blood, fighting ...
Biotechnology
Mar 27, 2026
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In the intricate machinery of the inner ear, hearing begins with a protein that moves a few billionths of a meter up to 100,000 times per second. That protein, called TMC1, sits at the tips of sensory hair cells deep in the ...
Evolution
Mar 25, 2026
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21
Scientists from National Taiwan University (NTU) and Linkou Chang Gung Memorial Hospital (CGMH) have developed a precision-engineered nanoplatform to conquer glioblastoma (GBM), the most aggressive and deadly form of brain ...
Bio & Medicine
Mar 25, 2026
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32
The blobfish, once considered the ugliest animal in the world, has since had quite the redemption arc. Years after it was first discovered, scientists realized that the deep-sea creature appeared so unnervingly blobby only ...
Cell & Microbiology
Mar 23, 2026
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