Biomolecules, as physical systems, are distinct molecular entities synthesized or utilized by living organisms that exhibit specific structural, thermodynamic, and dynamical properties enabling biological function. They include nucleic acids, proteins, lipids, carbohydrates, and diverse metabolites, each characterized by defined covalent connectivity, three-dimensional conformations, and interaction potentials with solvents, ions, and other biomolecules. Their behavior is governed by quantum-mechanical bonding, classical electrostatics, and statistical thermodynamics, leading to emergent phenomena such as self-assembly, allostery, enzyme catalysis, and molecular recognition. In physical systems research, biomolecules are studied through techniques like spectroscopy, crystallography, cryo-EM, and molecular simulations to elucidate structure–function relationships and energy landscapes.
Researchers from the National University of Singapore (NUS) have discovered that cancer cells do not simply push through surrounding tissues to spread, but instead actively grip onto protective tissue barriers and pull them ...
Cell & Microbiology
May 12, 2026
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For the first time, scientists at University of Leeds reveal a complex mechanism behind blood clotting. The findings, published in Science Advances, visualize a key component of blood clotting—platelet myosin—and how it is ...
Cell & Microbiology
May 5, 2026
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Scientists at Durham University, working in partnership with Jagiellonian University in Poland, have developed a new nanoscale tool that can capture and precisely position some of the most important proteins in the human ...
Bio & Medicine
Apr 30, 2026
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Each year, 20 million people are diagnosed with cancer. Various organs can be affected, and cancer types sometimes differ greatly at the cellular and molecular level. In about half of all cases, however, the protein p53 is ...
Molecular & Computational biology
Apr 29, 2026
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Until now, molecular-level DNA circuits have mainly been used for simple tasks, such as detecting the presence of cancer-related substances. However, these systems have faced a key limitation: once a reaction occurs, the ...
Bio & Medicine
Apr 27, 2026
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A team of scientists has identified a new physical mechanism that could help explain one of the most persistent mysteries in science: why life consistently uses one "handed" version of its molecules and not the other. In ...
Bio & Medicine
Apr 22, 2026
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Fluorescent probes have transformed modern biology by allowing researchers to tag and visualize individual molecules in living cells, tissues, and animals. Using these tools, researchers can watch viruses infect cells in ...
Cell & Microbiology
Apr 22, 2026
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Invisible "dark matter"—what cosmologists call the mysterious glue that holds everything together—is estimated to make up more than a quarter of the universe. In chemistry, dark matter refers to the thousands of small molecules ...
Molecular & Computational biology
Apr 21, 2026
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Engineers interested in creating artificial cells to deliver drugs to unhealthy parts of the body face a key challenge: for a cell-like system to move, change shape, or divide, it needs a way to generate force on command.
Biotechnology
Apr 19, 2026
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30
Researchers at University College Dublin have discovered a previously unknown "courier system" that cells use to deliver coherent biological messages between each other, opening new possibilities for medicine and biotechnology. ...
Cell & Microbiology
Apr 16, 2026
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