Biomolecules, as physical systems, are distinct molecular entities synthesized or utilized by living organisms that exhibit specific structural, thermodynamic, and dynamical properties enabling biological function. They include nucleic acids, proteins, lipids, carbohydrates, and diverse metabolites, each characterized by defined covalent connectivity, three-dimensional conformations, and interaction potentials with solvents, ions, and other biomolecules. Their behavior is governed by quantum-mechanical bonding, classical electrostatics, and statistical thermodynamics, leading to emergent phenomena such as self-assembly, allostery, enzyme catalysis, and molecular recognition. In physical systems research, biomolecules are studied through techniques like spectroscopy, crystallography, cryo-EM, and molecular simulations to elucidate structure–function relationships and energy landscapes.
Graphene-based olfactory sensors that can detect odor molecules based on the design of peptide sequences were recently demonstrated by researchers at Tokyo Tech. The findings indicated that graphene field-effect transistors ...
Bio & Medicine
Jan 19, 2023
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Chirality is essential for life, which can be observed in biological systems hierarchically from the molecular level to macromolecules and higher ordered nanostructures, such as 3D enzymes and micrometer cell membranes. Chirality ...
Nanophysics
Nov 7, 2022
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90
Rutgers University scientists have developed an analytical toolkit to measure the binding forces of single proteins when they are pulled away from their substrate—such as an enzyme—that will help the development of new nanomaterials, ...
Bio & Medicine
Oct 13, 2022
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140
Genomic sequencing has revolutionized our understanding of medicine and evolution, such as identifying hereditary anomalies. Arrays of nanometer-sized holes—nanopores—in silicon nitride can in principle dramatically speed ...
Bio & Medicine
Oct 5, 2022
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70
In the world of biomolecules, none is more iconic, nor more versatile, than DNA. Nature uses the famous double helix to store the blueprints of all living forms, drawing on a four-letter alphabet of nucleotides.
Bio & Medicine
Oct 4, 2022
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106
Constructing a tiny robot from DNA and using it to study cell processes invisible to the naked eye.... You would be forgiven for thinking it is science fiction, but it is in fact the subject of serious research by scientists ...
Bio & Medicine
Jul 28, 2022
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267
A research group led by Prof. Wu Aiguo at the Ningbo Institute of Materials Technology and Engineering (NIMTE) of the Chinese Academy of Sciences (CAS), in cooperation with Prof. Dan Larhammar's group at Uppsala University, ...
Bio & Medicine
May 11, 2022
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82
In a proof-of-concept study, researchers have created self-assembled, protein-based circuits that can perform simple logic functions. The work demonstrates that it is possible to create stable digital circuits that take advantage ...
Nanophysics
Apr 28, 2022
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486
Proteins are among the most versatile and ubiquitous biomolecules on earth. Nature uses them for everything from building tissues to regulating metabolism to defending the body against disease.
Nanomaterials
Feb 24, 2022
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192
Researchers at ICMAB present a study on new nanovesicles, known as quatsomes, which have been successfully engineered to encapsulate and deliver microRNAs for the treatment of tumors. These nanovesicles are produced by a ...
Bio & Medicine
Feb 4, 2022
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