Research news on Biomolecules

Biomolecules, as physical systems, are distinct molecular entities synthesized or utilized by living organisms that exhibit specific structural, thermodynamic, and dynamical properties enabling biological function. They include nucleic acids, proteins, lipids, carbohydrates, and diverse metabolites, each characterized by defined covalent connectivity, three-dimensional conformations, and interaction potentials with solvents, ions, and other biomolecules. Their behavior is governed by quantum-mechanical bonding, classical electrostatics, and statistical thermodynamics, leading to emergent phenomena such as self-assembly, allostery, enzyme catalysis, and molecular recognition. In physical systems research, biomolecules are studied through techniques like spectroscopy, crystallography, cryo-EM, and molecular simulations to elucidate structure–function relationships and energy landscapes.

Proteins can be selectively controlled with radio waves

In a significant advance in biological quantum sensing, a research team led by the Technical University of Munich (TUM) has discovered and tested a new mechanism of action in which proteins can be controlled with radio waves. ...

First human SMUG1 atomic snapshots reveal how cells repair DNA

Researchers have captured the first atomic structures of human SMUG1, an enzyme that helps cells repair damaged DNA. The findings provide new insight into how cells recognize and remove harmful DNA bases, and may support ...

Scientists unveil ten-year roadmap for building synthetic cells

Scientists from six Asian countries have launched an ambitious 10-year effort to build synthetic cells from non-living molecules, marking the region's first coordinated push to create an artificial single-celled biological ...

Molecular net boosts the power of natural biopesticides

Scientists at VIB and Vrije Universiteit Brussel have uncovered a previously unknown mechanism that helps a widely used biological pesticide become more effective. The study, published in Nature Communications, reveals how ...

Decoding the balance between life-and-death proteins

In every organism, the regulation of cell populations is a constant process. This balance relies on a continuous interplay between "guardian" proteins that promote cell survival and "killer" proteins that trigger programmed ...

Discovery could reshape RNA editing with DNA-guided CRISPR

A team of engineers at the University of Florida has developed a new form of CRISPR technology that could make diagnostics and treatments safer, more precise, and more affordable, while opening the door to entirely new ways ...

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