Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
Like its namesake, Janelia's GENIE Project Team makes wishes come true. Luckily for biologists, this genie doesn't grant just three requests.
Biotechnology
Sep 17, 2025
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20
Scientists at Feinberg are reshaping scientific understanding of the cell's tiniest components—structures once thought to be static, now revealed to be dynamic engines of cellular life. As they probe the inner workings of ...
Cell & Microbiology
Sep 16, 2025
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90
Scientists from the Trinity Biomedical Sciences Institute (TBSI) have discovered how nanoplastics—even smaller than microplastics—disrupt energy metabolism in brain cells. Their findings may have implications for better understanding ...
Bio & Medicine
Sep 15, 2025
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210
If you've ever accidentally sliced yourself on broken glass or a piece of paper, you may have noticed that the bleeding can be hard to stop. Scientists have long wondered how the cascade of events that leads to blood clotting ...
Biotechnology
Sep 12, 2025
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68
The process referred to as "nonsense-mediated mRNA decay" (NMD) is responsible for quality control in all cells of the body. This process monitors messenger RNAs (mRNA), which carry the blueprints for proteins. If errors ...
Cell & Microbiology
Sep 11, 2025
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46
A research team led by Prof. Liu Xuncheng from the South China Botanical Garden of the Chinese Academy of Sciences has recently published a study in the journal Plant Communications that sheds new light on the pathways that ...
Plants & Animals
Sep 10, 2025
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23
During his Ph.D. at UMass, Nikhil Malvankar was laser-focused on quantum mechanics and the movement of electrons in superconductors. Now a professor at Yale, the native of Mumbai, India, has pivoted toward biology to explain ...
Quantum Physics
Sep 9, 2025
2
304
A new study from Aarhus University shows that our cells' ability to clean out old protein clumps, known as aggregates, also includes a—up till now unknown—partnership with an engine that breaks down bigger pieces into smaller ...
Cell & Microbiology
Sep 9, 2025
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136
In human cells, there are about 20,000 genes on a two-meter DNA strand—finely coiled up in a nucleus about 10 micrometers in diameter. By comparison, this corresponds to a 40-kilometer thread packed into a soccer ball. Despite ...
Biotechnology
Sep 9, 2025
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94
Imagine being able to flip a light switch to control disease pathways inside a living cell. A team of visionary researchers at the Texas A&M University Health Science Center (Texas A&M Health) is making this dream a reality ...
Biotechnology
Sep 9, 2025
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21
