Research news on Biomolecular & subcellular processes

Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.

Video: How are we so good at folding proteins?

Proteins carry out almost every important function in our body, from copying our DNA to turning the food we eat into energy. These tiny "molecular machines" are first made by our cells as straight chains, like long pieces ...

Acidic nanoparticles target Parkinson's at cellular source

Inside every human cell, a tiny structure called a lysosome acts like a recycling center, breaking down toxic waste, clearing damaged proteins and helping keep the cell functioning properly. When that recycling center stops ...

How Argonaute, a key protein for RNA therapeutics, becomes activated

RNA therapeutics have emerged as one of the most promising new classes of medicines. Eight small interfering RNA (siRNA) drugs have already been approved worldwide for the treatment of genetic diseases, yet scientists have ...

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