Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.
The nucleolus is a liquid-like cellular organelle where protein factories called ribosomes are assembled. Researchers knew of three distinct compartments within the nucleolus, but how these compartments function to drive ...
Cell & Microbiology
18 hours ago
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6
Cells are crowded, dynamic places where thousands of molecules interact in tight quarters. Until now, scientists lacked a reliable way to see many of these molecular interactions as they happen. Researchers at the University ...
Cell & Microbiology
Jul 14, 2026
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Researchers have demonstrated a novel AI model that can predict which DNA molecules bind with other DNA molecules. A more thorough understanding of these hypercomplex binding relationships has utility in applications ranging ...
Molecular & Computational biology
Jul 14, 2026
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6
A team led by bioengineers at the University of California San Diego has developed a genome-scale reference map that details how individual genes control the functions and identities of human stem cells. This open-access ...
Biotechnology
Jul 13, 2026
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9
Inside the cell nucleus, genes must be turned on and off with precision to regulate biological processes. The first models of gene regulation were developed in the 1960s, yet modern science continues to uncover new layers ...
Cell & Microbiology
Jul 13, 2026
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A new Northwestern Medicine study published in the Proceedings of the National Academy of Sciences has explored the impacts of aging on essential cellular processes, findings that could shape the development of future anti-aging ...
Cell & Microbiology
Jul 9, 2026
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37
RNA has emerged as one of the most promising molecules in modern medicine, enabling advances from mRNA vaccines and gene therapies to genome editing and synthetic biology. However, designing RNA molecules that reliably fold ...
Biotechnology
Jul 8, 2026
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9
When a human cell prepares to split into two daughter cells, it must first construct a tiny internal machine called the mitotic spindle—a structure of protein fibers that physically pulls chromosomes apart and deposits one ...
Molecular & Computational biology
Jul 8, 2026
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6
Much of the genome is made up of repetitive DNA sequences that trace back to ancient mobile elements, many of which have lost their ability to copy themselves into new locations but can still cause problems if they become ...
Cell & Microbiology
Jul 8, 2026
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6
Researchers from UNSW Sydney have built the first artificial protein motor capable of taking controlled, directional steps along a DNA track. The protein, dubbed Tumbleweed, moves by alternating between three "feet" that ...
Bio & Medicine
Jul 6, 2026
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