Research news on Biomolecular & subcellular processes

Biomolecular and subcellular processes constitute a research area focused on the molecular mechanisms and dynamic interactions that underlie cellular function, organization, and regulation at nanometer to micrometer scales. It encompasses studies of protein folding and trafficking, nucleic acid structure and metabolism, signal transduction, membrane transport, organelle biogenesis, cytoskeletal dynamics, and macromolecular complex assembly. This field integrates biochemical, biophysical, structural, imaging, and computational approaches to quantify reaction kinetics, spatial organization, and emergent behaviors within cells, aiming to relate molecular-level events to higher-order cellular phenotypes, robustness, and dysfunction in contexts such as development, stress responses, and disease.

Artificial cells reveal how living ones take shape

Using simple artificial cells, a research group led by Makito Miyazaki of the RIKEN Center for Integrative Medical Sciences (IMS) in Japan has uncovered fundamental physical principles that govern how living cells change ...

Newly discovered mechanism protects DNA during cell division

Every time a cell divides, it must accurately copy and distribute its DNA between two new cells. However, in some cases, chromosomes do not fully separate, leaving behind thin strands of DNA known as DNA bridges that connect ...

How an embryo draws the line between body and germline

Every embryo of an organism that reproduces sexually faces an early and consequential decision: which of its cell lineages will make up the mortal body, and which will become the germline, the lineage that eventually makes ...

Bacteria may identify a virus without recognizing its DNA

When a virus enters a cell, its top priority is to replicate its genome rapidly, creating new viruses to infect elsewhere. The host has the opposite priority: to destroy the virus, ideally before it can do any harm. Biology ...

Scientists solve mystery of how muscle cells grow and stay healthy

In a study published in Nature Communications biophysicists unravel the mystery of how muscles form at the molecular level and maintain their function. The findings may help design treatments for muscle diseases such as dilated ...

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