Biological network methods are computational and statistical techniques used to construct, analyze, and interpret networks that represent biological entities (such as genes, proteins, metabolites, or cells) and their interactions or associations. These methods encompass network inference (e.g., from omics data using correlation, mutual information, or Bayesian approaches), network topology analysis (centrality, modularity, community detection), and network-based modeling of dynamics (e.g., Boolean or differential equation models). They are applied to identify functional modules, key regulators, and pathways, integrate multi-omics datasets, and support predictions of system behavior, disease mechanisms, and potential therapeutic targets within complex biological systems.
A research team led by Potsdam-based bioinformatician Prof. Dr. Zoran Nikoloski has developed a computational approach and an accompanying tool that enables the detailed analysis and reconstruction of actin filamentous structures ...
Plants & Animals
Mar 30, 2026
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Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three dimensions (3D). To better understand ...
Cell & Microbiology
Mar 9, 2026
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Can students be on the front lines of conservation? A new Canada-wide study, published in Metabarcoding and Metagenomics, suggests they can. The efforts of some 5,000 students produced data detailed enough to reveal complex ...
Ecology
Feb 23, 2026
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Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing the synthetic gene circuits ...
Cell & Microbiology
Nov 7, 2025
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Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today—knowing a gene's sequence does not automatically reveal what it does. Even in simple, well-studied bacteria ...
Cell & Microbiology
Oct 6, 2025
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30
To study growth-defense trade-offs in the context of metabolism in crops, scientists from the Universities of Potsdam and Erlangen, Max Planck Institute of Molecular Plant Physiology, and the National Institute of Biology, ...
Molecular & Computational biology
Aug 11, 2025
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17
In May 2022, the Facility for Rare Isotope Beams (FRIB) at Michigan State University (MSU), launched its precision measurement program. Staff from FRIB's Low Energy Beam and Ion Trap (LEBIT) facility take high-energy, rare-isotope ...
General Physics
Jun 3, 2024
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