Biological network methods are computational and statistical techniques used to construct, analyze, and interpret networks that represent biological entities (such as genes, proteins, metabolites, or cells) and their interactions or associations. These methods encompass network inference (e.g., from omics data using correlation, mutual information, or Bayesian approaches), network topology analysis (centrality, modularity, community detection), and network-based modeling of dynamics (e.g., Boolean or differential equation models). They are applied to identify functional modules, key regulators, and pathways, integrate multi-omics datasets, and support predictions of system behavior, disease mechanisms, and potential therapeutic targets within complex biological systems.
Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at NUS have developed a new method that allows scientists to better understand how DNA is organized and regulated inside cells. The study, published ...
Molecular & Computational biology
Jul 6, 2026
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10
In a first, a large, international team led by multiple labs at Harvard Medical School and Princeton University has published a complete wiring diagram of all the connections between neurons in the central nervous system ...
Cell & Microbiology
Jun 14, 2026
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101
Scientists at the Icahn School of Medicine at Mount Sinai have created a new artificial intelligence (AI) model that helps reveal how genes function together inside human cells, offering a powerful new way to understand biology ...
Cell & Microbiology
May 21, 2026
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19
Neurons, the uber-connected nerve cells that act as a main switchboard for the brain, are central to some incredibly complicated processes. They make it possible to think, walk, speak, and breathe. They even have built-in ...
General Physics
May 18, 2026
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127
What are the first steps that chart the path for a cell to become a blood cell, neuron cell, or pigment cell? Scientists have developed increasingly powerful tools to track those changes, but one challenge has persisted: ...
Cell & Microbiology
May 11, 2026
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21
A research team led by Potsdam-based bioinformatician Prof. Dr. Zoran Nikoloski has developed a computational approach and an accompanying tool that enables the detailed analysis and reconstruction of actin filamentous structures ...
Plants & Animals
Mar 30, 2026
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4
Scientists usually study the molecular machinery that controls gene expression from the perspective of a linear, two-dimensional genome—even though DNA and its bound proteins function in three dimensions (3D). To better understand ...
Cell & Microbiology
Mar 9, 2026
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Can students be on the front lines of conservation? A new Canada-wide study, published in Metabarcoding and Metagenomics, suggests they can. The efforts of some 5,000 students produced data detailed enough to reveal complex ...
Ecology
Feb 23, 2026
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11
Genetic engineers can design and assemble sophisticated gene circuits to program cells with new functions, but important signaling molecules can become diluted as these cells grow and divide, causing the synthetic gene circuits ...
Cell & Microbiology
Nov 7, 2025
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32
Despite rapid advances in reading the genetic code of living organisms, scientists still face a major challenge today—knowing a gene's sequence does not automatically reveal what it does. Even in simple, well-studied bacteria ...
Cell & Microbiology
Oct 6, 2025
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