Bioinformatics is a computational and analytical technique that applies algorithms, statistical methods, and database technologies to the acquisition, storage, processing, and interpretation of biological data, particularly large-scale omics datasets such as genomes, transcriptomes, and proteomes. It encompasses sequence alignment, gene prediction, variant calling, structural modeling, functional annotation, and systems-level network analysis. Bioinformatics pipelines integrate heterogeneous data types, automate quality control, and support reproducible research through workflow management and version-controlled code. As a technique, it enables hypothesis generation, biomarker discovery, and rational design in fields including molecular biology, genomics, pharmacology, and systems biology by transforming raw high-throughput experimental outputs into interpretable, quantitative biological insight.
Analyzing single-cell RNA sequencing (scRNA-seq) data is crucial for understanding complex biological processes and disease development, but identifying individual cell types within these vast datasets has been a significant ...
Cell & Microbiology
Sep 11, 2025
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24
Artificial intelligence is now better than humans at identifying many patterns, but evolutionary relationships have always been difficult for the technology to decipher. A team from the Bioinformatics Department at Ruhr University ...
Evolution
Sep 10, 2025
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36
Researchers from the Belgian Federal Institute Sciensano, as part of the DARWIN project, have developed a proof-of-concept for next generation detection methods of genome-edited organisms.
Biotechnology
Sep 8, 2025
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21
Biologists and computational scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory recently refined two artificial intelligence (AI) programs originally built by Meta, the company that owns Facebook, ...
Molecular & Computational biology
Sep 8, 2025
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31
In June, Google DeepMind took the wraps off AlphaGenome, its latest machine learning model for biological discovery. While DeepMind's Nobel Prize-winning AlphaFold model focuses on proteins and how they fold, AlphaGenome ...
Biotechnology
Sep 4, 2025
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33
Artificial intelligence relies on machine learning algorithms trained on massive datasets to make predictions—think of how ChatGPT learned language by gorging on the internet. In biology, however, scientists face a frustrating ...
Biotechnology
Sep 3, 2025
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84
Since its release in 2024, the open-source platform BindCraft, developed at EPFL, has already disrupted the world of protein design. Physical interactions between proteins influence anything from cell signaling and growth ...
Biotechnology
Aug 29, 2025
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44
When a tree dies, it forms the foundation for new life: In a slow, invisible process, leaves, wood and roots are gradually decomposed—not by wind or weather, but by millions and millions of tiny organisms.
Evolution
Aug 28, 2025
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43
New research from the Wisconsin Institute for Discovery is tackling a complex packing problem. Thanks to the development of a powerful new computational tool introduced in a study published in the journal Genome Research, ...
Biotechnology
Aug 28, 2025
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23
Tuberculosis (TB) is the world's deadliest infectious disease—and one of the hardest to cure. Standard treatment requires a cocktail of multiple drugs over at least six months, and one in five patients have a type of TB that ...
Biotechnology
Aug 25, 2025
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28
