Research news on Anatomic Variation

Anatomic variation, as a biological process, refers to the genetically and developmentally determined divergence in the form, size, position, or number of anatomical structures among individuals of the same species. It arises from coordinated molecular, cellular, and morphogenetic events during embryogenesis and postnatal growth, including differential gene expression, signaling gradients, and tissue patterning mechanisms that modulate organogenesis and body plan architecture. These variations are typically nonpathological and occur within a spectrum of species-typical phenotypes, contributing to phenotypic diversity, influencing physiological function, and modulating susceptibility to disease, surgical risk, and outcomes of diagnostic and interventional procedures.

Uncovering evolution at the center of cell division

Centromeres play virtually the same central role across the entire tree of life: They ensure the faithful segregation of chromosomes during cell division. Yet the striking diversity in centromere architecture—from large, ...

Beyond 'survival' of fittest: Evolution works in teams

Survival of the fittest. Nature red in tooth and claw. The common view of natural selection is based solely on the individual: A trait allows an organism to out-compete its rivals and is thus passed down to its offspring. ...

How chirality goes from the molecular level to the cellular one

RIKEN researchers have discovered how right-handed molecules in our cells can give rise to cells that are not symmetrical about their central axes. This discovery is a key step toward determining why most of our organs lack ...

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