21/10/2022

Prions induce toxic huntingtin oligomers

Neurodegenerative diseases like Alzheimer's, Parkinson's or Huntington's disease are characterized by the deposition of protein clumps, so-called protein aggregates, in the brains of patients. Even though disease-relevant ...

Embedding iron oxide into liposome bilayer to trigger ferroptosis

Ferroptosis, an iron-dependent regulated cell death process driven by excessive lipid peroxides and membrane injury, can enhance cancer vulnerability to chemotherapy. Lipid peroxidation of unsaturated lipids (UL) in biological ...

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