Urge to merge: Understanding how cells fuse

Scientists have known for a decade that cells that fuse with others to perform their essential functions—such as muscle cells that join together to make fibers—form long projections that invade the territory of their ...

Researchers use snake venom to solve structure of muscle protein

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction. The report, published today in Neuron, may lead to improved understanding of muscle-weakening ...

First structure of human cotransporter protein family member solved

In work that could someday improve treatments for epilepsy, UT Southwestern scientists have published the first three-dimensional structure of a member of a large family of human proteins that carry charged particles—ions—across ...

Newly identified bacteria-killing protein needs vitamin A to work

People who have inadequate vitamin A in their diets are more susceptible to skin infection, yet how that vitamin affects skin immunity has been unclear. In a study published today, UT Southwestern researchers shed some light ...

Scientists find method to boost CRISPR efficiency

Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.

3-D atomic structure of TRPML1 ion channel published

UT Southwestern Medical Center researchers today published a 3-D atomic structure of the ion channel found in mammals that is implicated in a rare, inherited neurodegenerative disease in humans. The work marks the first ...

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