Howard Hughes Medical Institute

Solving the Hox Specificity Paradox

The remarkable diversity of anatomical features along the body axis of animals—the differences between the head, the thorax and the abdomen, for example—is determined by proteins in the Hox family. But ...

dateJan 22, 2015 in Biotechnology
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Protein recycling machine visualized

Howard Hughes Medical Institute (HHMI) scientists have new structures of an essential cellular recycling machine that depict its structure with near atomic-level detail. The structures, which show a protein ...

dateJan 13, 2015 in Cell & Microbiology
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The TALE of new tools to study gene regulation

In nearly every organism's genome, scattered between genes that encode proteins, long regulatory regions stretch across expanses of DNA. Understanding what role these so-called enhancer regions play in controlling the activation ...

dateJul 01, 2013 in Biotechnology
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