Over a decade ago, Shinya Yamanaka and Kazutoshi Takahashi made a discovery that would revolutionize biomedical research and trigger the field of regenerative medicine. They learned how to reprogram human adult cells into ...
Cell & Microbiology
Apr 10, 2018
0
121
In a scientific first, researchers at the Gladstone Institutes turned skin cells from mice into stem cells by activating a specific gene in the cells using CRISPR technology. The innovative approach offers a potentially simpler ...
Biotechnology
Jan 18, 2018
0
800
After decades of research aiming to understand how DNA is organized in human cells, scientists at the Gladstone Institutes have shed new light on this mysterious field by discovering how a key protein helps control gene organization.
Biotechnology
May 18, 2017
0
45
How do you improve a Nobel Prize-winning discovery? Add a debilitating disease-causing gene mutation.
Cell & Microbiology
Oct 24, 2016
0
48
Combining the two most powerful biological tools of the 21st century, scientists at the Gladstone Institutes have modified how the genome of induced pluripotent stem cells (iPSCs) is read for the first time using a variation ...
Biotechnology
Mar 10, 2016
4
207
Scientists at the Gladstone Institutes have discovered that three transcription factors—proteins that direct gene expression—interact with each other and the genome to influence how a heart forms in an embryo. Without ...
Cell & Microbiology
Feb 11, 2016
0
10
What does it mean to be human? According to scientists the key lies, ultimately, in the billions of lines of genetic code that comprise the human genome. The problem, however, has been deciphering that code. But now, researchers ...
Biotechnology
Nov 10, 2013
1
0
An enzyme is a tiny, well-oiled machine. A class of proteins that are made up of multiple, interlocking molecular components, enzymes perform a variety of tasks inside each cell. However, precisely how these components work ...
Cell & Microbiology
Aug 8, 2013
0
0
Scientists at the Gladstone Institutes have mapped the precise frequency by which genes get turned on across the human genome, providing new insight into the most fundamental of cellular processes—and revealing new clues ...
Cell & Microbiology
Oct 8, 2012
0
0
Scientists at the Gladstone Institutes have discovered that environmental factors critically influence the growth of a type of stem cell--called an iPS cell--that is derived from adult skin cells. This discovery offers newfound ...
Cell & Microbiology
Jul 5, 2012
0
0
